OP30.05: The prevalence of sonographic signs of adenomyosis in women attending a medical screening facility

The prevalence of adenomyosis in low-risk healthy women is not known. Our aim was to assess the prevalence of sonographic signs of adenomyosis in a population of women attending a medical screening facility using transvaginal ultrasound and validated 2D sonographic signs. Women attending the facility underwent a gynecological examination and transvaginal ultrasound, using a Voluson P8 system with a 2D 7.5 MHz probe. Diagnosis of adenomyosis was made in the presence of any three of the following: asymmetrical myometrial thickening, linear striations, myometrial cysts, hyperechoic islands, irregular endometrial-myometrial junction (EMJ), parallel shadowing, and localised adenomyomas. 109 women were included with median age 47 (35–77), BMI 23.8 (16.9-35.3), parity 3 (0–6). 37 (33.9%) were postmenopausal (since menopause 10.3 ± 7.1 years). Prevalence of sonographic signs in table 1. The presence of 3 or more sonographic signs increased with age OR 5.6 (95% CI 2.1-9.0, p = 0.002), and decreased with years since menopause Pearson = −0.463 (p = 0.004). The strongest correlations with age were seen for asymmetrical myometrial thickening, myometrial cysts, hyperechoic islands, linear striations, and irregular EMJ (all p < 0.05). Among postmenopausal women, there was a strong inverse correlation with time since menopause for all signs except irregular EMJ (all < 0.05). Sonographic signs of adenomyosis are prevalent and increase with age during premenopause in a healthy nonselective screening population. Signs may persist through menopause but their prevalence decreases with time. All N = 109 Premenopausal N = 72 Postmenopausal N = 37