THC vape use patterns and device features: Observations from user-posted videos

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This study aimed to characterize the puff duration of people who use THC vapes by analyzing publicly available YouTube videos. Additional observations included device type, liquid composition, and notable user behaviors. Methods YouTube was systematically searched using predefined search terms related to THC vaping. Videos published between 2018 and 2024 were screened for inclusion based on clear visibility of puffing events. A total of 100 videos were included in the analysis. Puff initiation and termination were defined by visible facial muscle contraction and relaxation, respectively. Puff duration was determined using frame-by-frame analysis. Results The mean puff duration obtained from 456 analyzed puffs was 3.68 seconds with no significant differences between cartridge and disposable devices (p =0.1). Behavioral observations included engagement in extended puffing, coughing, and subjective description of aerosol harshness and flavor. Conclusions The observed puff durations during THC vape use closely aligned with those previously reported for electronic nicotine delivery systems (ENDS), suggesting that ENDS puffing regimens may be appropriate for preliminary emissions testing of THC vape products. However, distinct user behaviors reported in this study highlight the need for THC vape specific protocols that reflect real-word use patterns. 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F1000Research 2025, 14 :1325 ( https://doi.org/10.12688/f1000research.172683.1 ) NOTE: If applicable, it is important to ensure the information in square brackets after the title is included in all citations of this article. Close Copy Citation Details Export Export Citation Sciwheel EndNote Ref. Manager Bibtex ProCite Sente EXPORT Select a format first Track Share ▬ ✚ Brief Report THC vape use patterns and device features: Observations from user-posted videos [version 1; peer review: 1 not approved] Layla Shihadeh https://orcid.org/0009-0004-6341-3475 1 , Hadi Fares https://orcid.org/0009-0007-1460-5800 1 , Mario El Hourani https://orcid.org/0000-0001-7176-6175 1 Layla Shihadeh https://orcid.org/0009-0004-6341-3475 1 , Hadi Fares https://orcid.org/0009-0007-1460-5800 1 , Mario El Hourani https://orcid.org/0000-0001-7176-6175 1 PUBLISHED 27 Nov 2025 Author details Author details 1 American University of Beirut, Beirut, Beirut Governorate, Lebanon Layla Shihadeh Roles: Conceptualization, Data Curation, Formal Analysis, Methodology, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing Hadi Fares Roles: Conceptualization, Data Curation, Formal Analysis, Methodology, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing Mario El Hourani Roles: Conceptualization, Data Curation, Formal Analysis, Methodology, Supervision, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing OPEN PEER REVIEW DETAILS REVIEWER STATUS This article is included in the Addiction and Related Behaviors gateway. Abstract Background Tetrahydrocannabinol (THC) vaping has become increasingly prevalent, yet available empirical data on puffing behavior during THC vape use remain limited. This study aimed to characterize the puff duration of people who use THC vapes by analyzing publicly available YouTube videos. Additional observations included device type, liquid composition, and notable user behaviors. Methods YouTube was systematically searched using predefined search terms related to THC vaping. Videos published between 2018 and 2024 were screened for inclusion based on clear visibility of puffing events. A total of 100 videos were included in the analysis. Puff initiation and termination were defined by visible facial muscle contraction and relaxation, respectively. Puff duration was determined using frame-by-frame analysis. Results The mean puff duration obtained from 456 analyzed puffs was 3.68 seconds with no significant differences between cartridge and disposable devices ( p =0.1). Behavioral observations included engagement in extended puffing, coughing, and subjective description of aerosol harshness and flavor. Conclusions The observed puff durations during THC vape use closely aligned with those previously reported for electronic nicotine delivery systems (ENDS), suggesting that ENDS puffing regimens may be appropriate for preliminary emissions testing of THC vape products. However, distinct user behaviors reported in this study highlight the need for THC vape specific protocols that reflect real-word use patterns. READ ALL READ LESS Keywords THC, vaping, puff duration Corresponding Author(s) Mario El Hourani ( [email protected] ) Close Corresponding author: Mario El Hourani Competing interests: No competing interests were disclosed. Grant information: The author(s) declared that no grants were involved in supporting this work. Copyright: © 2025 Shihadeh L et al . This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. How to cite: Shihadeh L, Fares H and El Hourani M. THC vape use patterns and device features: Observations from user-posted videos [version 1; peer review: 1 not approved] . F1000Research 2025, 14 :1325 ( https://doi.org/10.12688/f1000research.172683.1 ) First published: 27 Nov 2025, 14 :1325 ( https://doi.org/10.12688/f1000research.172683.1 ) Latest published: 27 Nov 2025, 14 :1325 ( https://doi.org/10.12688/f1000research.172683.1 ) Introduction The use of tetrahydrocannabinol vapes (THC vapes) has become widespread across diverse populations. For example, past month use prevalence was found to be 12.8% among 13–17-year-olds in New England, 1 and 21.3% among electronic nicotine delivery system (ENDS) users aged 11-18 in a US nationally representative sample. 2 This sustained level of THC vaping is particularly notable following the 2019 outbreak of vaping-associated lung injuries, where most affected individuals reported using THC-containing products. 3 For many years, laboratories have used standardized puffing regimens to assess toxicant emissions from tobacco products. 4 – 6 Because toxicant yields are highly sensitive to puffing parameters, 7 , 8 knowledge of device-specific puffing behaviors is essential for accurate emissions testing. However, such information for THC vaping devices remains limited. Emerging studies have either applied ENDS puffing regimens, 9 or used protocols developed for cannabis joints, 10 yet it remains unclear whether these regimens reflect actual use patterns for THC vapes. To address this gap, we examined puff topography associated with THC vaping by analyzing publicly posted YouTube videos. We focused primarily on puff duration, while also documenting device types, liquid composition, and notable user behaviors. Methods We identified THC vape review videos and extracted information regarding device type, liquid composition, user behaviors, and puff duration. Video sourcing and screening We used the search terms “THC e-cigarette review,” “THC cartridge review,” “E-cig THC,” “THC vape unboxing,” and “THC vape review.” Inclusion criteria required videos to feature at least one individual visibly using a THC vaping device and to be published between 2018 and 2024. Videos were excluded if the vaping process was obscured by special effects, altered speeds, or interruptions. If a video featured multiple products, puff duration was analyzed separately for each. When two people used the same device, their data were grouped as a single dataset. We analyzed the first 100 videos that met these criteria. Puff duration measurement Videos were sorted chronologically by sourcing date and analyzed directly on YouTube using a frame-by-frame tool. The frame rate for each video was determined, and the number of frames per puff was converted to seconds. Puff initiation was defined by visible facial muscle contraction after device insertion; puff termination was defined by facial muscle relaxation or device removal, whichever occurred first. When devices included a light indicator, its activation coincided with facial contraction, supporting the method’s reliability. Consecutive puffs separated by less than 0.5 seconds were combined. One research team member measured puff duration for all videos. To assess reliability, a second member, blinded to the first member’s results, independently analyzed 25 randomly selected videos. Other information recorded We documented product type and liquid composition, based on visible labels or, when absent, manufacturer or reseller websites located via Google Image Search. During video analysis, we also recorded instances of coughing, double-puffing, and attempts to trigger a device’s puff time limiter (i.e., the “blinker challenge”). Statistical analysis Descriptive statistics (mean, median, interquartile range, minimum, and maximum) were used to summarize puff durations by device type. Independent t -tests were applied to compare cartridge and disposable products, and paired t -tests were used to assess interrater reliability in the reanalyzed subset. Statistical significance was set at p < 0.05. Results In typical videos, reviewers unboxed and presented the device, took one or more puffs, and described the effects experienced. Devices were either pre-filled cartridges designed for external batteries or disposables combining battery and cartridge (see Figure 1 ). Reviewers prioritized describing cannabinoid and terpene composition, with delta-8 THC being most frequently reported. Other THC types mentioned included THCP, THCA, THCO, and delta-10. Figure 1. Representative THC vaping devices observed in the analyzed YouTube videos, categorized as cartridge-based systems requiring external batteries (left) and disposable all-in-one units (right). Presenters often took short, rapid succession clearing puffs before inhalation. In disposable devices, several attempted the “blinker challenge,” drawing until the device’s LED light blinked to signal the puff duration limit. They frequently commented on vapor harshness and expressed a preference for smooth aerosols, describing flavors as “sweet,” “earthy,” or “cannabis-like.” Coughing after inhalation was common. After vaping, presenters assessed the intensity and onset speed of the psychoactive effects. Of the 98 individuals observed, 87 appeared to be male. Across the 100 videos, 456 puffs were analyzed. Puff durations ranged from 0.12 to 18.01 seconds, with a mean of 3.68 seconds. The 25th percentile puff duration was 1.85 seconds, the median was 2.94 seconds, and the 75th percentile was 4.39 seconds. In the subset of 25 randomly selected videos, the second rater recorded a mean puff duration of 3.85 seconds compared to 3.68 seconds for the original rater; paired t-test analysis showed no statistically significant difference ( p = 0.7). Table 1 summarizes puff durations by device type. No statistically significant difference in puff duration was found between cartridge and disposable products ( p = 0.1). The raw data supporting these findings, including puff duration measurements from 100 publicly available YouTube videos and the reanalysis of 25 randomly selected videos by a second rater to assess measurement reliability, are available in the Mendeley Data repository. 11 Table 1. Measured puff duration (sec) using video frame analysis. Q1: first quartile (25th percentile); Q3: third quartile (75th percentile). Cartridge Disposable All products N 58 42 100 Average 3.87 3.45 3.68 Median 3.23 2.69 2.94 Q1 2.06 1.63 1.85 Q3 4.43 4.35 4.39 Minimum 0.12 0.57 0.12 Maximum 18.01 12 18.01 Discussion This study was conducted to address the lack of empirical data regarding puff duration during the use of cannabis vaping products, a critical factor for laboratory toxicant emissions testing. A secondary aim was to explore product attributes valued by users. By analyzing 100 YouTube videos of cannabis vape product reviews posted between 2018 and 2024, we were able to characterize puff topography and user preferences in a real-world context. Our findings revealed a mean puff duration of 3.68 ± 2.66 seconds across 456 puffs. These results align closely with prior research. 12 Self-reported puff duration data from an online survey completed by 557 respondents (75% identified as male), with a mean puff duration of 5.1 ± 2.5 seconds among the 293 individuals who vaped cannabis liquids. In a separate study, Smith et al. (2024) 13 directly measured puff topography from 9 participants over two weeks using a cannabis oil vaping device (Gram1™) equipped with an integrated puff counter and puff duration sensor, finding individual mean puff durations ranging from 2.20 to 6.95 seconds, with a population mean of 4.06 seconds. Importantly, the mean puff duration identified in our study is also comparable to those documented for users of electronic nicotine delivery systems (ENDS). For instance, Hua et al. (2013) 14 reported a mean puff duration of 4.3 ± 1.5 seconds in a sample of 64 individuals, and clinical studies of ENDS users have documented mean durations between 3.5 ± 1.4 seconds 15 and 4.16 ± 1.06 seconds. 16 These similarities suggest that existing ENDS puffing regimens may offer a reasonable initial model for laboratory emissions testing of THC vaping products. However, further research tailored specifically to cannabis vapes is warranted to confirm this applicability, given differences in device design, liquid composition, and pharmacology. A notable limitation of this study is the underrepresentation of female users among the video presenters: 87 of the 98 individuals appeared male. This demographic imbalance contrasts with recent survey data showing comparable past-month THC vape use rates between women (39.9%) and men (38.1%), 17 suggesting limits to generalizability. Additional limitations include potential selection bias inherent to analyzing public video content, variability in video quality, and reliance on visual indicators of puff events. Qualitative observations from the video analyses provided further insights into user priorities. Presenters frequently emphasized the importance of flavor characteristics, throat hit smoothness, and the rapid onset and intensity of pharmacological effects. Additionally, the “blinker challenge,” in which users attempt to trigger a device’s maximum puff duration limit, emerged as a common behavioral feature. This suggests that device features may function similarly to “Easter eggs”, hidden features that reward users with a sense of achievement for longer puffs and, consequently, higher drawn doses. This phenomenon warrants further investigation given its potential implications for user exposure and behavior. In conclusion, this study contributes empirical data on THC vaping behaviors and emphasizes the need for laboratory protocols that accurately reflect real-world usage patterns. Ethical considerations This study did not involve human participants recruitment, or identifiable private information and therefore did not require ethical approval or informed consent. All data were obtained from publicly accessible YouTube videos that are freely available for viewing without restriction. No personal or identifiable information about individuals was collected, recorded, or analyzed. The study adhered to the ethical principles of using publicly available data for research and complies with F1000Research editorial policies. Reporting guidelines Mendeley Data. STROBE checklist for ‘THC vape use patterns and device features: Insights from user-posted videos’. DOI: 10.17632/sbzz2hj3xb.1. https://data.mendeley.com/datasets/sbzz2hj3xb/1 . 18 Data are available under the terms of the Creative Commons Zero “No rights reserved” data waiver (CC0 1.0 Public domain dedication). Data availability Mendeley Data: THC_VAPE_PUFF_DURATION. DOI: 10.17632/gx856tzfdr.3 https://data.mendeley.com/datasets/gx856tzfdr/3 . 11 This project contains the following underlying data: • THC_Puff Duration_Raw.xlsx (Puff duration data extracted from 100 publicly available YouTube videos of THC vape use, including search keywords, device type, upload year, and puff duration.) • THC_Puff Duration_Reanalyzed.xlsx (Subset of 25 randomly selected videos independently reanalyzed by a second rater to assess measurement reliability, including the percent difference in average puff duration between raters.) List of videos available upon reasonable request. Researchers interested in accessing the video list may contact the corresponding author at [email protected] . Requests must include a brief description of the intended use and will be granted provided that they align with the ethical requirements governing the study. Data are available under the terms of the Creative Commons Attribution 4.0 International license (CC-BY 4.0). References 1. Liu J, Winickoff JP, Hanby E, et al. : Prevalence and correlates of past 30-day dual-vaping of nicotine and cannabis among adolescents in five New England states. Drug Alcohol Depend. Jan 1 2024; 254 : 111055. PubMed Abstract | Publisher Full Text | Free Full Text 2. Dai HD, Subramanian R, Mahroke A, et al. : Prevalence and Factors Associated With Vaping Cannabidiol Among US Adolescents. JAMA Netw. Open. Aug 1 2023; 6 (8): e2329167. PubMed Abstract | Publisher Full Text | Free Full Text 3. Perrine CG, Pickens CM, Boehmer TK, et al. : Characteristics of a Multistate Outbreak of Lung Injury Associated with E-cigarette Use, or Vaping - United States, 2019. MMWR Morb. Mortal Wkly. Rep. Oct 4 2019; 68 (39): 860–864. PubMed Abstract | Publisher Full Text | Free Full Text 4. Shihadeh AL, Eissenberg TE: Significance of smoking machine toxicant yields to blood-level exposure in water pipe tobacco smokers. Cancer Epidemiol. Biomarkers Prev. Nov 2011; 20 (11): 2457–2460. PubMed Abstract | Publisher Full Text | Free Full Text 5. Goniewicz ML, Knysak J, Gawron M, et al. : Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tob. Control. Mar 2014; 23 (2): 133–139. PubMed Abstract | Publisher Full Text | Free Full Text 6. El-Hellani A, Adeniji A, Erythropel HC, et al. : Comparison of emissions across tobacco products: A slippery slope in tobacco control. Tob. Induc. Dis. 2024; 22 : 1–13. PubMed Abstract | Publisher Full Text | Free Full Text 7. Talih S, Balhas Z, Eissenberg T, et al. : Effects of user puff topography, device voltage, and liquid nicotine concentration on electronic cigarette nicotine yield: measurements and model predictions. Nicotine Tob. Res. Feb 2015; 17 (2): 150–157. PubMed Abstract | Publisher Full Text | Free Full Text 8. Beauval N, Verrièle M, Garat A, et al. : Influence of puffing conditions on the carbonyl composition of e-cigarette aerosols. Int. J. Hyg. Environ. Health. Jan 2019; 222 (1): 136–146. PubMed Abstract | Publisher Full Text 9. Sambiagio N, Guerra Iria DA, Auer R, et al. : Toxicological assessment of aerosols emitted by cannabis inhalation methods: Does cannabis vaping using Electronic NonNicotine Delivery Systems (ENNDS) and vaporizers reduce exposure to toxicants compared to cannabis smoking?2023. Reference Source 10. McClure EA, Stitzer ML, Vandrey R: Characterizing smoking topography of cannabis in heavy users. Psychopharmacology. Mar 2012; 220 (2): 309–318. PubMed Abstract | Publisher Full Text | Free Full Text 11. Hourani M: Data from: “THC_VAPE_PUFF_DURATION”. Mendeley Data. 2025; V3 . V3. Publisher Full Text 12. Morgan J, Gschwend G, Houston M, et al. : Vaping preferences of individuals who vaporise dry herb cannabis, cannabis liquids and cannabis concentrates. medRxiv. 2022:2022.04.23.22274223. Publisher Full Text 13. Smith JE, Aston ER, Farris SG: A preliminary characterization of cannabis oil use and vaporization among individuals who use for medical purposes: A pilot study. Exp. Clin. Psychopharmacol. Feb 2024; 32 (1): 35–44. PubMed Abstract | Publisher Full Text | Free Full Text 14. Hua M, Yip H, Talbot P: Mining data on usage of electronic nicotine delivery systems (ENDS) from YouTube videos. Tob. Control. Mar 2013; 22 (2): 103–106. PubMed Abstract | Publisher Full Text 15. St Helen G, Ross KC, Dempsey DA, et al. : Nicotine Delivery and Vaping Behavior During ad Libitum E-cigarette Access. Tob. Regul. Sci. Oct 2016; 2 (4): 363–376. PubMed Abstract | Publisher Full Text | Free Full Text 16. Spindle TR, Breland AB, Karaoghlanian NV, et al. : Preliminary results of an examination of electronic cigarette user puff topography: the effect of a mouthpiece-based topography measurement device on plasma nicotine and subjective effects. Nicotine Tob. Res. Feb 2015; 17 (2): 142–149. PubMed Abstract | Publisher Full Text | Free Full Text 17. McCauley DM, Baiocchi M, Gaiha SM, et al. : Sociodemographic differences in use of nicotine, cannabis, and non-nicotine E-cigarette devices. Drug Alcohol Depend. 2024/02/01/2024; 255 : 111061. PubMed Abstract | Publisher Full Text | Free Full Text 18. Hourani M: Mendeley Data. Data from: STROBE checklist for ‘THC vape use patterns and device features: Observations from user-posted videos’.2025; V1 . V1. Publisher Full Text Comments on this article Comments (0) Version 1 VERSION 1 PUBLISHED 27 Nov 2025 ADD YOUR COMMENT Comment Author details Author details 1 American University of Beirut, Beirut, Beirut Governorate, Lebanon Layla Shihadeh Roles: Conceptualization, Data Curation, Formal Analysis, Methodology, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing Hadi Fares Roles: Conceptualization, Data Curation, Formal Analysis, Methodology, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing Mario El Hourani Roles: Conceptualization, Data Curation, Formal Analysis, Methodology, Supervision, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing Competing interests No competing interests were disclosed. Grant information The author(s) declared that no grants were involved in supporting this work. Article Versions (1) version 1 Published: 27 Nov 2025, 14:1325 https://doi.org/10.12688/f1000research.172683.1 Copyright © 2025 Shihadeh L et al . This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Download Export To Sciwheel Bibtex EndNote ProCite Ref. Manager (RIS) Sente metrics Views Downloads F1000Research - - PubMed Central info_outline Data from PMC are received and updated monthly. - - Citations open_in_new 0 open_in_new 0 open_in_new SEE MORE DETAILS CITE how to cite this article Shihadeh L, Fares H and El Hourani M. THC vape use patterns and device features: Observations from user-posted videos [version 1; peer review: 1 not approved] . F1000Research 2025, 14 :1325 ( https://doi.org/10.12688/f1000research.172683.1 ) NOTE: If applicable, it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS track receive updates on this article Track an article to receive email alerts on any updates to this article. TRACK THIS ARTICLE Share Open Peer Review Current Reviewer Status: ? Key to Reviewer Statuses VIEW HIDE Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions Version 1 VERSION 1 PUBLISHED 27 Nov 2025 Views 0 Cite How to cite this report: lallai V. Reviewer Report For: THC vape use patterns and device features: Observations from user-posted videos [version 1; peer review: 1 not approved] . F1000Research 2025, 14 :1325 ( https://doi.org/10.5256/f1000research.190426.r440304 ) The direct URL for this report is: https://f1000research.com/articles/14-1325/v1#referee-response-440304 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 02 Jan 2026 Valeria lallai , University of California Irvine, Irvine, California, USA Not Approved VIEWS 0 https://doi.org/10.5256/f1000research.190426.r440304 The authors examine 100 publicly available videos showing one or more individuals vaping THC to analyze puff duration and related behaviors. The idea is interesting, especially given the need for more consistency across clinical and preclinical studies to better understand ... Continue reading READ ALL The authors examine 100 publicly available videos showing one or more individuals vaping THC to analyze puff duration and related behaviors. The idea is interesting, especially given the need for more consistency across clinical and preclinical studies to better understand THC vaping effects. However, the enthusiasm for the manuscript is limited. It is very concise, and the Introduction does not sufficiently prepare the reader to understand the study’s rationale or interpret the results. It lacks enough background to contextualize the research question. In the Methods, it’s unclear why data from two individuals using the same device are combined into one dataset. This raises questions about individual differences: is subject variability not relevant to behaviors like puff duration and quality? More justification is needed here. Table 1 compares two values at the 25th percentile, but the choice of this analysis method is unclear, and its justification in the context of standard statistical practice is not explained. Additional clarification is needed to understand the rationale and meaning of these analyses. The Discussion is very brief, and the second paragraph contains content that seems more suitable for the Results section, which itself is very limited. Consequently, the manuscript lacks substantial empirical data on THC vaping behavior, despite the implications of the title. Overall, while the study does not provide new empirical insights into THC vaping, it highlights the importance of developing laboratory protocols that more accurately reflect real-world usage. Is the work clearly and accurately presented and does it cite the current literature? No Is the study design appropriate and is the work technically sound? Partly Are sufficient details of methods and analysis provided to allow replication by others? No If applicable, is the statistical analysis and its interpretation appropriate? I cannot comment. A qualified statistician is required. Are all the source data underlying the results available to ensure full reproducibility? Partly Are the conclusions drawn adequately supported by the results? Partly Competing Interests: No competing interests were disclosed. Reviewer Expertise: Neurobiology and Behavior, addiction, basic science, animal models, neuroscience I confirm that I have read this submission and believe that I have an appropriate level of expertise to state that I do not consider it to be of an acceptable scientific standard, for reasons outlined above. Close READ LESS CITE CITE HOW TO CITE THIS REPORT lallai V. Reviewer Report For: THC vape use patterns and device features: Observations from user-posted videos [version 1; peer review: 1 not approved] . F1000Research 2025, 14 :1325 ( https://doi.org/10.5256/f1000research.190426.r440304 ) The direct URL for this report is: https://f1000research.com/articles/14-1325/v1#referee-response-440304 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Respond or Comment COMMENT ON THIS REPORT Comments on this article Comments (0) Version 1 VERSION 1 PUBLISHED 27 Nov 2025 ADD YOUR COMMENT Comment keyboard_arrow_left keyboard_arrow_right Open Peer Review Reviewer Status info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions Reviewer Reports Invited Reviewers 1 Version 1 27 Nov 25 read Valeria lallai , University of California Irvine, Irvine, USA Comments on this article All Comments (0) Add a comment Sign up for content alerts Sign Up You are now signed up to receive this alert Browse by related subjects keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2026 lallai V. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 02 Jan 2026 | for Version 1 Valeria lallai , University of California Irvine, Irvine, California, USA 0 Views copyright © 2026 lallai V. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (0) Not Approved info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions The authors examine 100 publicly available videos showing one or more individuals vaping THC to analyze puff duration and related behaviors. The idea is interesting, especially given the need for more consistency across clinical and preclinical studies to better understand THC vaping effects. However, the enthusiasm for the manuscript is limited. It is very concise, and the Introduction does not sufficiently prepare the reader to understand the study’s rationale or interpret the results. It lacks enough background to contextualize the research question. In the Methods, it’s unclear why data from two individuals using the same device are combined into one dataset. This raises questions about individual differences: is subject variability not relevant to behaviors like puff duration and quality? More justification is needed here. Table 1 compares two values at the 25th percentile, but the choice of this analysis method is unclear, and its justification in the context of standard statistical practice is not explained. Additional clarification is needed to understand the rationale and meaning of these analyses. The Discussion is very brief, and the second paragraph contains content that seems more suitable for the Results section, which itself is very limited. Consequently, the manuscript lacks substantial empirical data on THC vaping behavior, despite the implications of the title. Overall, while the study does not provide new empirical insights into THC vaping, it highlights the importance of developing laboratory protocols that more accurately reflect real-world usage. Is the work clearly and accurately presented and does it cite the current literature? No Is the study design appropriate and is the work technically sound? Partly Are sufficient details of methods and analysis provided to allow replication by others? No If applicable, is the statistical analysis and its interpretation appropriate? I cannot comment. A qualified statistician is required. Are all the source data underlying the results available to ensure full reproducibility? Partly Are the conclusions drawn adequately supported by the results? Partly Competing Interests No competing interests were disclosed. Reviewer Expertise Neurobiology and Behavior, addiction, basic science, animal models, neuroscience I confirm that I have read this submission and believe that I have an appropriate level of expertise to state that I do not consider it to be of an acceptable scientific standard, for reasons outlined above. reply Respond to this report Responses (0) lallai V. Peer Review Report For: THC vape use patterns and device features: Observations from user-posted videos [version 1; peer review: 1 not approved] . F1000Research 2025, 14 :1325 ( https://doi.org/10.5256/f1000research.190426.r440304) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/14-1325/v1#referee-response-440304 Alongside their report, reviewers assign a status to the article: Approved - the paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations - A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved - fundamental flaws in the paper seriously undermine the findings and conclusions Adjust parameters to alter display View on desktop for interactive features Includes Interactive Elements View on desktop for interactive features Competing Interests Policy Provide sufficient details of any financial or non-financial competing interests to enable users to assess whether your comments might lead a reasonable person to question your impartiality. 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