In Vitro Cytotoxic Effect of 2-(Morpholin-4-Yl)-4,5-Bis(2’’,2’’,2’’-Trinitroethoxy)-1,3,5-Triazine on Human Fibroblasts, Peripheral Blood Mononuclear Cells and Breast Cancer Cells
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This study evaluated the in vitro cytotoxicity of 2-(morpholin-4-yl)-4,5-bis(2’’,2’’,2’’-trinitroethoxy)-1,3,5-triazine on human fibroblasts, peripheral blood mononuclear cells, and breast cancer cells to determine its effective cytotoxic concentration.
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Abstract
2-(Morpholin-4-yl)-4,5-bis(2’’,2’’,2’’-trinitroethoxy)-1,3,5-triazine having QSAR-predicted anti-tumor activity was tested for the cytotoxicity using MTT and LDH cell viability tests. The experiments were conducted using human fibroblasts, peripheral blood mononuclear cells and breast cancer cells and allowed to identify effective cytotoxic concentration ant therapeutic range of this compound. The data obtained suggest the feasibility of the further studies of the test compound as a potential anti-cancer agent.
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- last seen: 2026-05-19T01:45:01.086888+00:00