Fusion Cryptography for Secure Medical Data Transmission Using Mathematical Quantum Computing Operations

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Alharbi, and 1 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-6498634/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 30 Sep, 2025 Read the published version in Scientific Reports → Version 1 posted 11 You are reading this latest preprint version Abstract With the growing demand for highly secure medical data transmission, this research introduces a fused cryptography framework that integrates mathematical quantum computing operations with advanced classical encryption techniques. The proposed method incorporates quantum principles, including quantum walks, quantum-based cyclic shift operators, quantum XOR operations, and quantum key image generation with classical methods such as bit-plane extraction and hyperchaotic system-based scrambling. A hyperchaotic map (HCM) generates random key sequences to produce both a spatial domain random image and a quantum key image. The medical image is first decomposed into eight bit-planes, and only the high-information bit-planes (HIBPs) undergo encryption to optimize computational efficiency. HIBPs are scrambled using multilayer, block-wise, and diagonal permutations based on the chaotic sequences. Quantum encryption is then applied, starting with NEQR (Novel Enhanced Quantum Representation) encoding, followed by Baker map-based scrambling and quantum XOR diffusion to secure the final ciphertext. Extensive experiments, including entropy evaluation, noise attack resilience, clipping attack robustness, and correlation analysis, confirm the superior security and performance of the proposed method. Notably, the algorithm achieves near-ideal results, such as an entropy of 7.9999, a correlation coefficient of 0.0001, 98% plaintext recovery after 30% noise corruption, and 96% recovery after 25% ciphertext clipping, demonstrating its robustness for secure medical data transmission. Physical sciences/Mathematics and computing/Computer science Physical sciences/Mathematics and computing/Information technology Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Published Journal Publication published 30 Sep, 2025 Read the published version in Scientific Reports → Version 1 posted Editorial decision: Revision requested 13 May, 2025 Reviews received at journal 12 May, 2025 Reviews received at journal 06 May, 2025 Reviewers agreed at journal 30 Apr, 2025 Reviewers agreed at journal 30 Apr, 2025 Reviewers agreed at journal 30 Apr, 2025 Reviewers invited by journal 29 Apr, 2025 Editor assigned by journal 24 Apr, 2025 Editor invited by journal 24 Apr, 2025 Submission checks completed at journal 23 Apr, 2025 First submitted to journal 21 Apr, 2025 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-6498634","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":450118635,"identity":"9050b041-c316-4ec1-99f5-ed1663fda7b2","order_by":0,"name":"Amer Aljaedi","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA2UlEQVRIie2OsQrCMBBArxQ6RbpWKO0vXCm4dPBXLA4ddRIHh5vsInTt56QEnIpdM1pcHRxdFE/F1egmmAcJF8jjHYDF8pO4hHwJ//HwPlKcpzIk9wvlngKUnyp+2dD8vMzCVM8knBYK4lK+V4I2p2TTFmKkp+DUOwXYTgwZmRMO1uqhuDwAgkGJu56Sy1WJtGblwkpc7d8rqHNKB6QEBqw4rIA2VBLdUxpuCxG0B2w2u0KgNlSibrpNjqts7Jd5vz8vsiiuDBXGw9ck+Qjjf8Y1LGKxWCx/zw3Vm0PEh+4j5AAAAABJRU5ErkJggg==","orcid":"","institution":"University of Tabuk","correspondingAuthor":true,"prefix":"","firstName":"Amer","middleName":"","lastName":"Aljaedi","suffix":""},{"id":450118636,"identity":"7a725d62-2800-44a8-a423-02898083a9fa","order_by":1,"name":"Sajjad Shaukat Jamal","email":"","orcid":"","institution":"King Khalid University","correspondingAuthor":false,"prefix":"","firstName":"Sajjad","middleName":"Shaukat","lastName":"Jamal","suffix":""},{"id":450118637,"identity":"da370c27-cd12-4b11-9ace-2f6b3c9a6022","order_by":2,"name":"Abdullah Aljuhni","email":"","orcid":"","institution":"University of Tabuk","correspondingAuthor":false,"prefix":"","firstName":"Abdullah","middleName":"","lastName":"Aljuhni","suffix":""},{"id":450118638,"identity":"a03a8ed5-0005-4b53-9e97-212ed338fe15","order_by":3,"name":"Adel R. 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