Pten, a protean tumor suppressor

G L Mutter, Mutter GL
The American Journal of Pathology · 2001 · vol. 158(6) , pp. 1895–8 · doi:10.1016/s0002-9440(10)64656-1 · PMID:11395362 · PMC1891981
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⚙ AI-generated summary by qwen3.7-flash, 2026-08-26 ⓘ

This review article characterizes PTEN as a versatile tumor suppressor, detailing its multifaceted roles in regulating cell growth and maintaining genomic stability.

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MeSH descriptors

Genes, Tumor Suppressor Neoplasms Phosphoric Monoester Hydrolases Protein Serine-Threonine Kinases Tumor Suppressor Proteins Humans Loss of Heterozygosity Mutation Neoplasm Metastasis Neoplasms Neoplasms Phosphoric Monoester Hydrolases Phosphoric Monoester Hydrolases Proto-Oncogene Proteins Proto-Oncogene Proteins Proto-Oncogene Proteins c-akt PTEN Phosphohydrolase

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europepmc
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pubmed
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