Clinical and anamnestic aspects of adenomyosis

In: Reproductive health of woman · 2025 · pp. 99–104 · doi:10.30841/2708-8731.5.2025.337958 · W4413771522
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AI-generated summary by claude@2026-06, 2026-06-08

This study analyzed 90 reproductive-aged women with adenomyosis, identifying burdened heredity, extragenital pathology, menstrual cycle disorders, and a history of gynecological interventions as potential predictors.

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AI-generated deep summary by claude@2026-06, 2026-06-09

This study conducted a clinical-statistical analysis of 90 reproductive-age women with adenomyosis and compared them with 30 gynecologically healthy reproductive-age controls, using a numeric pain scale to characterize illness features and identify potential predictors. Among women with adenomyosis, 88.9% had a burdened hereditary history, and the most frequent extragenital comorbidities were respiratory system disorders (46.7%) and gastrointestinal diseases (42.2%); clinically, 100.0% had menstrual cycle disturbances and dyspareunia was reported by 65.5%, with a history of inflammatory uterine/adnexal processes (52.2%) and cervical pathology (46.7%) also common. The paper reports reproductive and obstetric/anamnestic factors including high frequencies of induced abortion (77.8%), plus rates of spontaneous pregnancy loss (20.0%) and ectopic pregnancy (8.9%), and it lists prior intrauterine procedures such as endometrial scraping, hysteros resectoscopy, and various uterine or cervical/adjacent operations. The paper’s limitation is that it is based on a case-control statistical association rather than prospective causal testing, and it frames these factors as a “favorable background” for adenomyosis progression rather than proving causality. This paper is centrally about endometriosis and/or adenomyosis — it specifically focuses on adenomyosis clinical and anamnestic predictors in reproductive-age women.

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Abstract

The article presents the results of clinical and statistical analysis and identifies relevant aspects of adenomyosis in women of reproductive age.The objective: to study the clinical and statistical analysis of women of reproductive age with adenomyosis and its impact on the development of the disease.Materials and methods. A clinical and statistical analysis was conducted on 90 women of reproductive age with adenomyosis (main group) and 30 gynecologically healthy women of reproductive age (control group). A numerical rating scale was used to determine the intensity of pain.Results. The conducted clinical and statistical analysis of the examined groups allowed to determine possible predictors of adenomyosis in women of reproductive age. 88.9% of women have a burdened heredity. Concomitant extragenital pathology: respiratory system diseases were found in 46.7% of women, gastrointestinal tract diseases – in 42.2%. Patients of the main group had menstrual cycle disorders (100%) and decreased generative and sexual function (dyspareunia 65.5%). Burdened gynecological history included: inflammatory processes of the uterus and appendages – 52.2% of cases, pathology of the cervix – 46.7%, ovarian cysts – 15.6%; artificial abortions – 77.8%, spontaneous abortion – 20.0%, ectopic pregnancy – 8.9%. Intrauterine surgical interventions were performed: curettage of the uterine cavity – in 17.8% of women, hysteroresectoscopy – 21.1%, pathological childbirth (manual revision of the uterine walls, obstetric forceps, maternal birth trauma) – 25.6%, uterine surgery (cesarean section, suturing of the perforated hole) – 30%, appendage surgery – in 18.9%, cervical surgery – in 35.6%.Conclusions. Severe gynecological heredity, extragenital pathology, impaired immune mechanisms, hormonal imbalance, inflammatory diseases of the female genital organs, abortions, pathological childbirth, and intrauterine surgeries create a favorable background for the development and progression of adenomyosis.

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adenomyosisdyspareunia

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