Growth of an endometrial polyp in a postmenopausal patient using raloxifene

Hugo Maia, Amélia Maltez, Maíta Oliveira, Marta Almeida, Elsimar Metzker Coutinho
In: Gynaecological Endoscopy · 2000 · vol. 9(2) , pp. 117–121 · doi:10.1046/j.1365-2508.2000.00304.x · W2051176515
article OA: closed CC0
View on OpenAlex View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This case report describes an endometrial polyp with simple hyperplasia and p53 overexpression that developed in a postmenopausal patient using raloxifene for eight months.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Objective To describe the association of raloxifene use with the development of an endometrial polyp in a postmenopausal patient. Design Case report study. Results Hysterosonography and hysteroscopy showed the occurrence of an endometrial polyp in a postmenopausal patient who had been using raloxifene for 8 months. Pathological investigation showed the presence of simple hyperplasia in the polyp. Oestrogen receptors were present in both the polyp and the atrophic endometrium. Progesterone receptors, on the other hand, were detected mainly in the atrophic endometrium. There was a focal p53 overexpression in the glandular epithelium of the polyp. Conclusion Raloxifene stimulated the development of an endometrial polyp in this postmenopausal patient. The presence of progesterone receptors in the atrophic endometrium suggests an agonistic action of raloxifene on this tissue.

My notes (saved in your browser only)

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

References (9)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK