[Progesterone antagonists: biochemical and pharmacological aspects and clinical usefulness].

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AI-generated summary by gemini-2.5-flash-lite, 2026-08-08

Progesterone antagonists, while known for contraception and abortion, are also investigated for treating uterine fibroids, breast cancer, endometriosis, and meningiomas with generally beneficial outcomes.

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Abstract

Although classically the antiprogestins have been used for the control of pregnancy diseases and adrenal function, in the medical literature are a plenty of papers about the treatment with progesterone antagonists of leiomyoma, breast cancer, endometriosis and meningioma. The treatment is beneficial or mitigating in greatest number of cases, but they have other different uses than usual like contraception and abortion.

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Condition tags

endometriosis

MeSH descriptors

Hormone Antagonists Hormone Antagonists Hormone Antagonists Hormone Antagonists Mifepristone Mifepristone Mifepristone Mifepristone Progesterone Clinical Trials as Topic Female Humans Progesterone

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Source provenance

europepmc
last seen: 2026-09-21T06:08:07.822426+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:12:32.173627+00:00
License: CC0 · commercial use OK