Intestinal endometriosis mimicking Crohn's disease: a rare cause of nonspecific abdominal pain

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This clinical vignette presents a case of intestinal endometriosis mimicking Crohn's disease as a rare cause of nonspecific abdominal pain.

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AI-generated deep summary by qwen3.7-flash, 2026-08-29 · read from full text

This clinical vignette presents a case of intestinal endometriosis that clinically and radiologically mimicked Crohn's disease in a patient presenting with nonspecific abdominal pain. The authors highlight the diagnostic challenge posed by the overlapping symptoms and imaging features of these two distinct conditions, emphasizing the need for high clinical suspicion. The paper serves as a reminder that endometriosis can present with gastrointestinal manifestations that are easily misdiagnosed as inflammatory bowel disease without thorough evaluation. This paper is centrally about endometriosis — specifically deep infiltrating intestinal endometriosis that presents with symptoms resembling Crohn's disease.

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Abstract

CLINICAL VIGNETTEthe differential diagnosis of abdominal pain -a cornerstone of internal medicine practice.
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Abstract

Keywords

endometriosisabdominal painintestinal diseasesCrohn diseasediagnosisdifferential

References

- Jaramillo-Cardoso A, Shenoy-Bhangle AS, VanBuren WM, et al. Imaging of gastrointestinal endometriosis: what the radiologist should know. Abdom Radiol (NY). 2020; 45(6): 1694–1710. - Yantiss RK, Clement PB, Young RH. Endometriosis of the intestinal tract: a study of 44 cases of a disease that may cause diverse challenges in clinical and pathologic evaluation. Am J Surg Pathol. 2001; 25(4): 445–454. - Guadagno A, Grillo F, Vellone VG, et al. Intestinal endometriosis: mimicker of inflammatory bowel disease? Digestion. 2015; 92(1): 14–21. - Drobatz K. Acute abdominal pain in adults: evaluation and diagnosis. Am Fam Physician. 2023; 107(6): 585–596. - Dave HB, Chamié LP, Young SW, et al. Bowel endometriosis: systematic approach to diagnosis with US and MRI. Radiographics. 2025; 45(4): e240102.

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europepmc
last seen: 2026-09-21T06:08:07.822426+00:00
openalex
last seen: 2026-09-21T06:00:58.944781+00:00
pubmed
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