HYDROXAMIC ACID DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT

2001
OA: closed

Abstract

Hydroxamic acid derivatives represented by general formula (I), nontoxic salts thereof or prodrugs of the same (wherein each symbol is as defined in the description). Because of inhibiting the production of IL-6, the compounds of the general formula (I) are useful as preventives and/or remedies for various inflammatory diseases, sepsis, multiple myeloma, plasma cell leukemia, osteoporosis, cachexia, psoriasis, nephritis, kidney cell cancer, Kaposi's sarcoma, rheumatoid arthritis, hypergammaglobulinemia, Caslteman's disease, artial myxoma, diabetes, autoimmune diseases, hepatitis, colon inflammation, graft-versus-host disease, inflammation and endometriosis.

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europepmc
last seen: 2026-07-14T06:08:30.651965+00:00