Animal and cellular models of human disease

Arends MJ, Mark J. Arends, Eric S White, White ES, C Bruce A Whitelaw, Whitelaw CB
The Journal of Pathology · 2016 · vol. 238(2) , pp. 137–40 · doi:10.1002/path.4662 · PMID:26482929
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This review collection examines recent methodological and conceptual developments in genetically engineered, chemically induced, and naturally occurring animal and cellular disease models across a wide range of human conditions.

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Abstract

In this eighteenth (2016) Annual Review Issue of The Journal of Pathology, we present a collection of 19 invited review articles that cover different aspects of cellular and animal models of disease. These include genetically-engineered models, chemically-induced models, naturally-occurring models, and combinations thereof, with the focus on recent methodological and conceptual developments across a wide range of human diseases.

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MeSH descriptors

Disease Models, Animal Models, Biological Animals Fibrosis Genetic Diseases, Inborn Humans Immune System Diseases Inflammation Neoplasms Practice Guidelines as Topic Research Design

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europepmc
last seen: 2026-10-04T09:26:46.659050+00:00
pubmed
last seen: 2026-10-08T21:16:42.682428+00:00