Myxoid Change in Nondecidualized Cutaneous Endometriosis Resembling Malignancy

Ying AJ, A J Ying, Alan J. Ying, Copeland LJ, Larry J. Copeland, L J Copeland, Arif Hameed, A Hameed, Hameed A
Gynecologic Oncology · 1998 · vol. 68(3) , pp. 301–303 · doi:10.1006/gyno.1998.4952 · PMID:9570985 · W2001394561
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This paper describes myxoid change in nondecidualized cutaneous endometriosis that can mimic malignancy on histopathological examination.

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Abstract

Cutaneous endometriosis infrequently arises in the absence of pelvic disease. Rare features such as myxoid change can resemble malignancy and may pose a challenging histological diagnosis. We are not aware of any previous cases involving nondecidualized cutaneous endometriosis with myxoid change associated with an abdominal surgical scar. We report the first such case in which a 24-year-old woman presented with a steadily growing, firm, tender, painful, subcutaneous cicatrical mass that had appeared shortly after cesarean section 1 year previously. The mass was removed and permanent sections revealed foci of large, irregular endometrial glands embedded within prominent myxoid stroma and acellular mucin pools, with fibrosis and pseudoinfiltration of the fascia. No evidence of malignancy was identified. This case demonstrates that nondecidualized cutaneous endometriosis with myxoid change should be considered in the differential diagnosis of histologically similar malignancies such as mucinous adenocarcinoma and pseudomyxoma peritonei.

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Condition tags

endometriosis

MeSH descriptors

Endometrial Neoplasms Endometrial Neoplasms Endometriosis Endometriosis Myxoma Skin Diseases Skin Diseases Skin Neoplasms Skin Neoplasms Adult Diagnosis, Differential Endometrial Neoplasms Endometriosis Female Humans Myxoma Skin Diseases Skin Neoplasms

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (7)

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