Comparison of the effect of Elaeagnus angustifolia flower capsule and sildenafil citrate tablet female sexual interest/arousal disorder in clinical trial study

Sanaz Zeinalzadeh, Abdolali Mohagheghzadeh, Fatemeh Ahmadinezhad, Marzieh Akbarzadeh
In: Journal of Family Medicine and Primary Care · 2019 · vol. 8(11) , pp. 3614–3620 · doi:10.4103/jfmpc.jfmpc_525_19 · PMID:31803662 · W2987725723
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Abstract

Background and Aims: Sexual desire is one of the main issues affecting people's individual and social life. The present study aimed to compare the effects of Elaeagnus angustifolia extract and sildenafil citrate tablet on female sexual interest/arousal disorder (FSIAD) among the women referring to health centers in 2013. Methods: In this randomized clinical trial, 125 women between 18 and 40 years old who suffered from FSIAD were divided into Elaeagnus angustifolia, sildenafil citrate, and control groups. The study data were gathered using Female Sexual Function Index (FSFI) and through measurement of TSH and prolactin. The first intervention group had to consume 4.5 g Elaeagnus angustifolia in two divided doses for 35 days and the second one had to use 50 mg sildenafil citrate tablets for 4 weeks one hour before their sexual relationships. On the other hand, the control group was required to consume the placebo. The data were analyzed using the SPSS statistical software (v. 18) and P < 0.05 was considered as statistically significant. Results: The frequency of sexual interest/arousal before the intervention was 53.7%, 50. %, and 66.7% in the Elaeagnus angustifolia, sildenafil citrate, and control groups, respectively ( P = 0.269). However, these measures were respectively obtained as 19.5%, 33.3%, and 52.4% after the intervention ( P = 0.007). Conclusion: Both interventions were effective in improvement of sexual interest/arousal. Yet, further studies are required to be conducted on the issue. Therefore, direct examination of health care providers, identifying and diagnosing sexual problems are the most important primary care. Influences the process of couples’ sexual problems.

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