Lipoxins: a novel regulator in embryo implantation.

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This paper hypothesizes that lipoxins, known for resolving inflammation, may act as novel regulators of embryo implantation through specific molecular mechanisms.

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Abstract

Embryo implantation is essential for mammalian pregnancy, which involves intricate cross-talk between the blastocyst and the maternal endometrium. Recent advances have identified various molecules crucial to implantation and endometrial receptivity, including leukemia inhibitory factor, calcitonin, and homeobox A10. There is a close relationship between implantation and inflammation. Lipoxins, important in the resolution of inflammation, may be a potential regulator in implantation. Here we discuss the hypothesis that lipoxins may work as a novel regulator in embryo implantation and the possible molecular mechanisms.

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europepmc
last seen: 2026-08-03T06:10:56.557307+00:00
unpaywall
last seen: 2026-05-21T05:10:58.409756+00:00
License: CC-BY-4.0