A Presentation of Synchronous Ovarian and Endometrial Endometrioid Adenocarcinoma From a Case of Suspected Ruptured Ectopic Pregnancy

Siak Ming Goh, Yanlin Carly Wu, Ryan Wai Kheong Lee
In: Journal of Medical Cases · 2023 · vol. 14(1) , pp. 31–35 · doi:10.14740/jmc4011 · PMID:36755996 · PMC9881485 · W4317396213
article OA: gold CC0
📄 Open PDF View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

A young woman presenting with symptoms of ruptured ectopic pregnancy was diagnosed with synchronous ovarian and endometrial endometrioid adenocarcinoma, necessitating completion staging surgery and chemotherapy.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This case report describes a 32-year-old woman who underwent laparoscopic surgery for suspected ruptured ectopic pregnancy based on elevated serum β-human chorionic gonadotropin, acute abdominal pain, per vaginal bleeding, and ultrasound findings consistent with pelvic free fluid and an adnexal mass. Unexpectedly, histology revealed synchronous ovarian and endometrial endometrioid adenocarcinoma, prompting completion staging surgery and adjuvant chemotherapy because fertility-sparing surgery was considered unsuitable. The paper emphasizes that while ruptured ectopic pregnancy is a leading concern, ovarian malignancy is a rare differential diagnosis in acute abdomen presentations, and it notes fertility-sparing surgery might be considered for selected young patients without synchronous gynecologic cancers. This paper is centrally about endometriosis or adenomyosis? No—it does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via keyword match due to the “endometrioid” terminology.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

A 32-year-old woman of child-bearing age who initially underwent surgical laparoscopy for suspected ruptured ectopic pregnancy with elevated serum β-human chorionic gonadotropin (hCG) levels was unexpectedly found to have histologically diagnosed synchronous ovarian and endometrial endometrioid adenocarcinoma. She subsequently underwent another full completion staging surgery and adjuvant chemotherapy as she was unsuitable for fertility-sparing surgery. An elevated serum β-hCG level accompanied by clinical signs of acute abdominal pain, per vaginal bleeding, ultrasound features of abdominal free fluid in the pelvis and an adnexal mass warrants a high clinical suspicion for a ruptured ectopic pregnancy. However, it is important to recognize ovarian malignancy as a rare but differential diagnosis to suspected ectopic pregnancy in patients with acute abdomen. Fertility-sparing surgery may be considered for young patients seeking fertility, without compromising patient survival in women without synchronous gynecological cancers.

My notes (saved in your browser only)

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (3)

References (17)

Source provenance

europepmc
last seen: 2026-06-28T06:08:18.748782+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK