Abdominal wall endometriosis: accuracy of the diagnostic triad

In: International Journal of Reproduction, Contraception, Obstetrics and Gynecology · 2015 · pp. 1417–1421 · doi:10.18203/2320-1770.ijrcog20150722 · W1793433154
article OA: diamond CC0 ⤵ 2 in-corpus citations
AI-generated summary by gemini-2.5-flash-lite, 2026-06-07

This study found that a history of Cesarean section, along with scar swelling and pain, are key diagnostic indicators for abdominal wall endometriosis.

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This retrospective observational study from a tertiary hospital assessed the prevalence, clinicopathological presentation, and diagnostic accuracy of criteria for abdominal wall endometriosis (AWE) by analyzing 493 patients with genital endometriosis using medical record data, symptom-by-symptom sensitivity/specificity, likelihood ratios, and penalized logistic regression. Clinically diagnosed AWE occurred in 45 cases (8.3%), and histology confirmed AWE in 41, with 4 showing suture granuloma, supporting a diagnostic triad of pain plus swelling at the scar site with previous low segment cesarean section (LSCS) where pain, swelling, and previous LSCS had sensitivity 71% and specificity 100%. The symptom presentation occurred within 6 years after LSCS, with an odds ratio of 19 (95% CI 1.7–1595; P=0.016), and the paper explicitly notes that previous LSCS was the only contributing factor in their regression analysis. This paper is centrally about endometriosis — specifically abdominal wall endometriosis and the accuracy of a diagnostic symptom triad after cesarean scar surgery.

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Abstract

Background: Endometriosis is the presence of endometrial glands and stroma outside the uterine cavity and musculature. The objectives were to study the prevalence, the clinic-pathological presentation and the accuracy of the criteria for diagnosis of abdominal wall endometriosis.Methods: This is a retrospective observational study done at a tertiary hospital. The study was approved by the ethics committee and the IRB. Data was retrieved from computer generated medical records. Specificity, sensitivity and likelihood ratio along with univariate and multivariable penalized logistic regression analysis of each presenting symptom were done.Results: Of the 493 cases with genital endometriosis, 45 cases had AWE diagnosed clinically giving a prevalence of 8.3%. Histological diagnosis of AWE was made in 41, while 4 had suture granuloma. Pain, swelling and previous LSCS had sensitivity of 71%, specificity of 100% and the likelihood ratio was 0.29. The presentation was within 6 years after the index surgery of Caesarean section, with the odds ratio of having endometriosis of 19 (95% CI 1.7- 1595) and the P value of 0.016.Conclusions: The diagnostic triad of previous caesarian section with swelling and pain at the scar site should prompt the possibility of AWE. However, previous LSCS was the only factor that contributed to the presence of abdominal wall endometriosis.
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Background

Endometriosis is the presence of endometrial glands and stroma outside the uterine cavity and musculature. The objectives were to study the prevalence, the clinic-pathological presentation and the accuracy of the criteria for diagnosis of abdominal wall endometriosis.

Methods

This is a retrospective observational study done at a tertiary hospital. The study was approved by the ethics committee and the IRB. Data was retrieved from computer generated medical records. Specificity, sensitivity and likelihood ratio along with univariate and multivariable penalized logistic regression analysis of each presenting symptom were done.

Results

Of the 493 cases with genital endometriosis, 45 cases had AWE diagnosed clinically giving a prevalence of 8.3%. Histological diagnosis of AWE was made in 41, while 4 had suture granuloma. Pain, swelling and previous LSCS had sensitivity of 71%, specificity of 100% and the likelihood ratio was 0.29. The presentation was within 6 years after the index surgery of Caesarean section, with the odds ratio of having endometriosis of 19 (95% CI 1.7- 1595) and the P value of 0.016.

Conclusions

The diagnostic triad of previous caesarian section with swelling and pain at the scar site should prompt the possibility of AWE. However, previous LSCS was the only factor that contributed to the presence of abdominal wall endometriosis. Metrics

References

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