Significance of diminished hormone expression in nulligravida woman presenting with triad of uterine pathologies
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Abstract
Genital tract tuberculosis (TB) occurring together with adenomyosis and leiomyoma is rarely observed. A 40-year-old nulligravida woman was clinically diagnosed with the fibroid uterus. Histopathological examination revealed leiomyoma with adenomyosis and TB. Immunohistochemistry for oestrogen and progesterone receptors was performed to determine their expression, which was found to be moderate, although it was expected to be strongly positive. This case is being reported because of its rare coexistence of these conditions; moreover, it suggests that reduced hormone expression, particularly of oestrogen, may enhance the severity of TB, ultimately resulting in adverse reproductive outcomes.
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Cites (2)
- Functional Implications of Estrogen and Progesterone Receptors Expression in Adenomyosis, Potential Targets for Endocrinological Therapy 2022
- Pattern and frequency of endometrial and ovarian pathologies with adenomyosis uteri in patients who attended the tertiary care hospital among rural population of North India 2015
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