Ovarian teratoma mimicking metastasis on I-131 scan : a case report

Case report OA: closed
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-07-16 ⓘ

A case report describes a mature cystic teratoma in the pelvic region that mimicked metastasis on an I-131 scan in a patient treated for differentiated thyroid cancer.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-07, 2026-07-16 · read from full text ⓘ

This paper is a case report describing a postoperative whole-body I-131 scan done for well-differentiated thyroid cancer, focusing on a false-positive iodine uptake in the pelvic region. In a patient under thyroid cancer postoperative surveillance, the suspected metastatic focus was incidentally diagnosed as a mature cystic teratoma rather than metastatic disease. The report emphasizes that accurate interpretation of I-131 scans is important because uptake can be falsely positive in unrelated organs and disease processes, potentially leading to unnecessary interventions. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

The whole body I-131 scan is routinely performed in the postoperative treatment of patients with well-differentiated thyroid cancer. Accurate interpretation of whole body I-131 scan after thyroidectomy is critical to appropriate management of patients with thyroid cancer, to prevent unnecessary surgical removal or exposure to radioiodine. Unfortunately, false-positive uptakes in several other organs and their associated disease processes have been reported. We report a case of false-positive iodine uptake in the pelvic region with incidentally diagnosed mature cystic teratoma.
Full text 3,710 characters · extracted from oa-doi-fallback · 2 sections · click to expand

Abstract

The whole body I-131 scan is routinely performed in the postoperative treatment of patients with well-differentiated thyroid cancer. Accurate interpretation of whole body I-131 scan after thyroidectomy is critical to appropriate management of patients with thyroid cancer, to prevent unnecessary surgical removal or exposure to radioiodine. Unfortunately, false-positive uptakes in several other organs and their associated disease processes have been reported. We report a case of false-positive iodine uptake in the pelvic region with incidentally diagnosed mature cystic teratoma.

References

Brown AP, Greening WP, McCready VR, Shaw HJ, Harmer CL. Radioiodine treatment of metastatic thyroid carcinoma: the Royal Marsden Hospital experience. Br J Radiol. 1984;57(676):323–7. Filetti S, Bidart JM, Arturi F, Caillou B, Russo D, Schlumberger M. Sodium/iodide symporter: a key transport system in thyroid cancer cell metabolism. Eur J Endocrinol. 1999;141(5):443–57. Carlisle MR, Lu C, McDougall IR. The interpretation of 131I scans in the evaluation of thyroid cancer, with an emphasis on false positive findings. Nucl Med Commun. 2003;24(6):715–35. Shapiro B, Rufini V, Jarwan A, Geatti O, Kearfott KJ, Fig LM, et al. Artifacts, anatomical and physiological variants, and unrelated diseases that might cause false-positive whole-body 131-I scans in patients with thyroid cancer. Semin Nucl Med. 2000;30(2):115–32. Byeong-Cheol Ahn. Physiologic and False Positive Pathologic Uptakes on Radioiodine whole Body Scan. In: Rongfu Wang editor. 12 Chapters on Nuclear Medicine. Kindle edition. Intech ; 2012. p.1–24. Nair N, Basu S, Pakhale H. Unusual uptake of radioiodine in the chest in a patient with thyroid carcinoma. Br J Radiol. 2004;77(913):63–7. Riesco–Eizaguirre G, Santisteban P. A perspective view of sodium iodide symporter research and its clinical implications. Eur J Endocrinol. 2006;155(4):495–512. Ghander C, Lussato D, Conte Devolx B, Mundler O, Taieb D. Incidental diagnosis of struma ovarii after thyroidectomy for thyroid cancer: functional imaging studies and follow-up. Gynecol Oncol. 2006;102(2):378–80. Utsunomiya D, Shiraishi S, Kawanaka K, Lwakatare F, Tomiguchi S, Kido R, et al. Struma ovarii coexisting with mucinous cystadenoma detected by radioactive iodine. Clin Nucl Med. 2003;28(9):725–7. Song HJ, Xue YL, Xu YH, Qiu ZL, Luo QY. Abnormal 131I uptake in a benign serous ovarian cystadenoma mimicking bladder physiological uptake. Clin Nucl Med. 2012;37(3):e59–60. Lungo M, Tenenbaum F, Chaumerliac P, Vons C, Mirat A, Beuzen F, et al. Ovarian endometriosis cyst with iodine 131 uptake: first case of false positive in the follow up for differentiated thyroid carcinoma. Ann Endocrinol (Paris). 2000;61(2):147–50. Logani S, Baloch ZW, Snyder PJ, Weinstein R, LiVolsi VA. Cystic ovarian metastasis from papillary thyroid carcinoma: a case report. Thyroid. 2001;11(11):1073–5. Makani S, Kim W, Gab AR. Struma Ovarii with a focus of papillary thyroid cancer: a case report and review of the literature. Gynecol Oncol. 2004;94(3):835–9. Matsuda K, Maehama T, Kanazawa K. Malignant Struma Ovarii with Thyrotoxicosis. Gynecol Oncol. 2001;82(3):575–7. Outwater EK, Siegelman ES, Hunt JL. Ovarian teratomas: tumor types and imaging characteristics. Radiographics. 2001;21(2):475–90. Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Yoon, S., soo Hong, I. Ovarian Teratoma Mimicking Metastasis on I-131 Scan : A Case Report. Nucl Med Mol Imaging 47, 52–54 (2013). https://doi.org/10.1007/s13139-012-0167-3 Received: Revised: Accepted: Published: Issue date: DOI: https://doi.org/10.1007/s13139-012-0167-3

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

Source provenance

europepmc
last seen: 2026-10-11T09:27:45.537177+00:00
pubmed
last seen: 2026-10-08T21:13:42.918798+00:00