Abstracts of the Annual Meeting of the Iuliu Haţieganu, University of Medicine and Pharmacy : 3rd – 7th December 2018, Cluj-Napoca
Wild and cultured Thymus Marshallianus extracts improved antioxidant defense, reduced blood glucose, and alleviated anxiety-like behaviors in diabetic rats.
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This study evaluated the comparative effects of wild and cultured Thymus Marshallianus extracts on oxidative stress and behavioral changes in a diabetic rat model induced by streptozotocin. The researchers conducted in vitro experiments on human umbilical vein endothelial cells and in vivo trials using Wistar rats to assess biomarkers such as MDA, NF-kB, and HDAC1 alongside anxiety-like behaviors measured by open field and elevated plus maze tests. Results indicated that both extracts reduced blood glucose levels, enhanced antioxidant capacity in the frontal lobe, and significantly improved anxiety-like behavior by increasing time spent in open arms. This paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.
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