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子宮内膜症症例におけるマイクロバイオーム解析； 腹水と卵巣嚢腫内容液にマイクロバイオームは存在するのか？
http://hdl.handle.net/20.500.12000/0002018034
http://hdl.handle.net/20.500.12000/000201803471d91b23-83ea-4eaf-9f8d-d8763eace285
| 名前 / ファイル | ライセンス | アクション |
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iken540abstract.pdf (743 KB)
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iken540review.pdf (820 KB)
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iken540text.pdf (780 KB)
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| アイテムタイプ | 旧登録用アイテムタイプv1.0(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2022-06-10 | |||||||||
| タイトル | ||||||||||
| タイトル | Microbiome analysis in women with endometriosis: does a microbiome exist in peritoneal fluid and ovarian cystic fluid? | |||||||||
| 言語 | en | |||||||||
| タイトル | ||||||||||
| タイトル | 子宮内膜症症例におけるマイクロバイオーム解析； 腹水と卵巣嚢腫内容液にマイクロバイオームは存在するのか？ | |||||||||
| 言語 | ja | |||||||||
| 作成者 |
大石, 杉子
× 大石, 杉子
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| アクセス権 | ||||||||||
| アクセス権 | open access | |||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
| 権利情報 | ||||||||||
| 権利情報 | © 2022 The Authors | |||||||||
| 言語 | en | |||||||||
| 権利情報 | ||||||||||
| 権利情報 | This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. | |||||||||
| 言語 | en | |||||||||
| 主題 | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | 16S rRNA | |||||||||
| 主題 | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | endometriosis | |||||||||
| 主題 | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | microbiome | |||||||||
| 主題 | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | ovarian cystic fluid | |||||||||
| 主題 | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | peritoneal fluid | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | Purpose: To investigate the relationship between the microbiome of the female genital tract and endometriosis. Methods: This prospective cohort study included 36 women who underwent laparoscopic surgery for ovarian tumor from July 2019 to April 2020. Of them, 18 had endometriosis, and 18 did not have endometriosis. Vaginal secretions, endometrial fluid, peritoneal fluid, and ovarian cystic fluid were collected during surgery. Next-generation sequencing of bacterial 16S rRNA was performed to characterize the microbiome. Results: Specific microbiomes were not detected in either peritoneal fluid or ovarian cystic fluid regardless of the presence or absence of endometriosis and the type of cyst. When the cutoff value of infectious bacterial abundance in the vagina was set as 64.3%, there were many cases more than a cutoff value in the endometriosis group significantly (p = 0.01). When the cutoff value of infectious bacterial abundance in the endometrium was set as 18.6%, there were many cases more than a cutoff level in the endometriosis cases significantly (p = 0.02). Conclusion: Peritoneal fluid and ovarian cystic fluid are almost sterile, although dysbiosis may occur in the vaginal and endometrial microbiome in women with endometriosis. |
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| 言語 | en | |||||||||
| 出版者 | ||||||||||
| 出版者 | 琉球大学 | |||||||||
| 言語 | ja | |||||||||
| 出版者 | ||||||||||
| 出版者 | University of the Ryukyus | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||||
| 資源タイプ | doctoral thesis | |||||||||
| 出版タイプ | ||||||||||
| 出版タイプ | VoR | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
| 関連情報 | ||||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | https://doi.org/10.1002/rmb2.12441 | |||||||||
| 収録物識別子 | ||||||||||
| 収録物識別子タイプ | PISSN | |||||||||
| 収録物識別子 | 1445-5781 | |||||||||
| 収録物識別子 | ||||||||||
| 収録物識別子タイプ | EISSN | |||||||||
| 収録物識別子 | 1447-0578 | |||||||||
| 収録物名 | ||||||||||
| 収録物名 | Reproductive Medicine and Biology | |||||||||
| 言語 | en | |||||||||
| 書誌情報 |
巻 21, 号 1 |
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| 学位授与番号 | ||||||||||
| 学位授与番号 | 甲第540号 | |||||||||
| 学位名 | ||||||||||
| 学位名 | 博士(医学) | |||||||||
| 言語 | ja | |||||||||
| 学位授与年月日 | ||||||||||
| 学位授与年月日 | 2022-03-18 | |||||||||
| 学位授与機関 | ||||||||||
| 学位授与機関識別子Scheme | kakenhi | |||||||||
| 学位授与機関識別子 | 18001 | |||||||||
| 学位授与機関名 | 琉球大学 | |||||||||
| 言語 | ja |
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