Predicting Retinal Sensitivity Using Optical Coherence Tomography Parameters in Central Serous Chorioretinopathy

Purpose: To predict the change of retinal sensitivity using optical coherence tomography (OCT) parameters in eyes with central serous chorioretinopathy (CSC). Methods Twenty-three eyes of 23 patients with CSC were enrolled. Retinal sensitivity was measured twice with a microperimetry in all examined eyes. OCT measurement was simultaneously conducted. The relationship between retinal sensitivities and the thicknesses of i) retinal nerve fiver layer + ganglion cell layer (RNFL+GCL), ii) inner nuclear layer (INL) iii) outer nuclear layer (ONL) and iV) serous retinal detachment height (SRDH) were investigated in a point-wise manner. We also investigated the association between the change of retinal sensitivity and OCT parameters at baseline. Results The mean age of participants was 49.8 ± 10.7 years. The mean SRDH was significantly lower (p<0.001) and the mean retinal sensitivity (p<0.001) was significantly higher in the 2nd examination compared to the 1st measurements, however LogMAR visual acuity (VA) was not significantly different between the two measurements (p=0.063). LogMAR VA was associated with retinal sensitivity both in the 1st and 2nd measurements (p<0.001). The retinal sensitivity in the 2nd examination was significantly correlated with retinal sensitivity, RNFL+GCL, INL, ONL, SRDH in the 1st examination and the improvement of SRDH. Conclusions Retinal sensitivity was associated with retinal structure in eyes with CSC; these parameters were useful to predict the change of visual function before the treatment.