[Vaginal adenosis: A case report and literature review]

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This case report describes vaginal adenosis in a 42-year-old woman, highlighting its rare nature and potential progression to adenocarcinoma in DES-exposed patients.

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Abstract

We report a case of vaginal adenosis in a woman of 42years. This is a rare congenital disorder since cessation of use of diethylstilbestrol (DES), usually of benign course, not to ignore in its tubo-endometrial histological form which may progress to atypical adenosis precursor of vaginal clear cell adenocarcinoma in patients exposed in utero to DES.

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MeSH descriptors

Exocrine Glands Vaginal Diseases Adult Biopsy Cell Differentiation Diagnosis, Differential Diethylstilbestrol Diethylstilbestrol Exocrine Glands Female Humans Infertility, Female Infertility, Female Leiomyomatosis Leiomyomatosis Polyps Polyps Uterine Neoplasms Uterine Neoplasms Vaginal Diseases

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Source provenance

europepmc
last seen: 2026-08-30T09:23:35.175841+00:00
pubmed
last seen: 2026-05-13T22:20:54.390225+00:00
unpaywall
last seen: 2026-05-14T19:30:52.867331+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine