Effects of Tripterygium Wifordii Polyglycosidium on Rats with Experimental Endometriosis

Objective To explore the effect and mechanism of Tripterygium wifordii polyglycosidium(TWP) on the treatment of endometriosis.Methods To set up endometriosis model by rat self-endometria transplantation,and detect the influence of Tripterygium wifordii polyglycosidium on TNF-α,IL-6 and VEGF of endometriosis tissue.Results The pathogenesis of the endometriosis were inhibited by TWP(P0.05,P0.01).The contents of TNF-α,IL-6 and the expressed of VEGF of endometriosis tissue were inhibited by TWP(P0.05,P0.01).Conclusion TWP can inhibit the growth of endometrial transplants,which is relates with the depression of TNF-α,IL-6 and VEGF of endometriotic tissue.