子宫内膜异位症患者检测腹腔液及血清IL-4、IL-8价值分析
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Abstract
目的探讨子宫内膜异位症（endometriosis,EMS）患者腹腔液及血清中IL-4、IL-8的变化及意义.方法采用酶联免疫吸附双抗体夹心法（ELISA）检测48例内异症患者（Ⅰ～Ⅱ期21例,Ⅲ～Ⅳ期27例）及18例对照组（其他妇科手术,术中可见腹腔积液者）腹腔液及血清中IL-4、IL-8含量.结果子宫膜异位症组的腹腔液及血清IL-4、IL-8含量均高于对照组,差异有统计学意义（P〈0.05）;EMS组Ⅲ～Ⅳ期腹腔液IL-4、IL-8和血清均高于Ⅰ、Ⅱ期腹腔液和血清含量,差异均有统计学意义（P〈0.05）;EMS组术前后血清中IL-4、IL-8含量比较,差异有统计学意义（P〈0.05）.结论 IL-4、IL-8在EMS发病中起重要作用,检测其含量变化有助于该病的诊断和治疗.
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