51 year old patient with Familial Mediterranean fever (FMF), Type 2 Diabetes Mellites (T2DM) and Multiple Sclerosis (MS)- case report

Abstract Familial Mediterranean fever (FMF) is a genetic disorder that follows an autosomal recessive pattern and is characterized by recurrent episodes of febrile peritonitis, synovitis, and pleuritis. Many studies associate FMF with MS1. Multiple Sclerosis is the most common non-traumatic disabling disease affecting young adults.2 The cause of MS remains unclear, since MS is a complex disease, Inflammation, demyelination, and axonal degeneration are the major pathologic mechanisms that cause the clinical manifestations.3 Type 2 Diabetes Mellites( T2DM ) is considered to have the highest prevalence amongst other diseases affecting over 340 million people worldwide4 characterized with resistance to insulin and disrupted function for beta cell istle in the pancreas. Which together result in insufficient supply of insulin5. our patient is a 51-year-old male, that has FMF and T2DM and recently developed neurological symptoms related to MS, which is a very rare occurrence that urged us to do further testing and imaging which made the diagnosis clear it was MS. All three diseases co existing is the reason we wrote this case report, to shed the light on such abandoned cases for patients who might be diagnosed earlier if got regularly clinical tests.