New observations on endometrial physiology after transcervical injection of methylene blue dye

In: Fertility and Sterility · 2004 · vol. 82(6) , pp. 1700–1704 · doi:10.1016/j.fertnstert.2004.07.947 · PMID:15589887 · W2007092087
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Microhysteroscopy of methylene blue-stained endometrium revealed distinct gland and cell changes across the ovulatory cycle phases, potentially useful for infertile patients.

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Abstract

We describe the in vivo features of endometrium stained with methylene blue dye and observed via microhysteroscopy, showing the patterns of endometrial glands and superficial cell changes during the midproliferative, periovulatory, and midluteal phases. These preliminary observations have allowed us to identify a series of changes occurring in the different phases of the ovulatory cycle of potential value in reproductive medicine for specific groups of infertile patients.

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