Unique Immunological Profile In Patients With COVID-19
preprint
OA: gold
CC-BY-4.0
Abstract
Abstract The relationship between SARS-CoV-2 and host immunity is unknown. We show here that patients with COVID-19 had an altered immune phenotype, with an expansion of adaptive FceRIgneg NK cells, and inflammatory CD14+CD16+ monocytes. T cells were reduced and overexpressed the Tim-3 exhaustion molecule. Low frequencies of CD8 T cells and NKG2A+ NK cells, and expansion of mature CD57+ NK cells were associated with poor prognosis. These findings unveil a unique immunological profile in COVID-19 patients.
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- europepmc
- last seen: 2026-05-19T01:45:01.086888+00:00
- unpaywall
- last seen: 2026-05-21T05:10:58.409756+00:00
License: CC-BY-4.0