Erythema Elevatum Diutinum: A Neutrophilic Dermatosis Presenting as Bullae

Abstract Background: Erythema elevatum diutinum (EED) is a rare disease that is associated with streptococcal infection, blood disorders, and autoimmunity. It is a chronic inflammatory dermatosis in the spectrum of cutaneous leukocytoclastic vasculitis. Typical skin lesions include nodules, erythema, and plaques; however, the presence of blister lesions is rare, especially on the limbs. Case presentation: We report a rare case of EED that presented as blisters on both limbs and the trunk of a 62-year-old woman. She responded well to oral corticosteroid and hydroxychloroquine treatment. The lesions were significantly improved after 2 weeks of treatment. Conclusions: EED is a rare form of cutaneous vasculitis. It is a good mimic of other types of skin diseases because of its diverse clinical presentations. It can even rarely present as blisters.