AROMATASE INHIBITOR DIAGNOSIS AND THERAPY

The present invention provides pharmaceutical compositions which are useful for imaging and/or treating endometriosis. The compositions are useful for the treatment of reproductive age women, as well as post-menopausal women suffering from this disorder. The pharmaceutical composition is a liposome composition that includes a liposome carrier component that contains on its surface a moiety targeted for an endometriotic implant or leaky blood vessels within the implant. The inventive liposome composition includes an aromatase inhibitor and/or a radiolabeled complex encapsulated by the liposome component. A label capable of external detection can be included so as to permit the detection of an endometrial implant and/or diagnosis of the presence of endornetriosis in a patient. The label can be bound to the aromatase inhibitor. Alternatively, when the label is separate from the inhibitor, or when the inhibitor is not present, a radiolabeled complex can be included.