Third generation cognitive behavioural therapy versus treatment-as-usual for attention deficit and hyperactivity disorder: a randomized, 2-parallel-group, evaluator blinded, superiority trial

Abstract BackgroundThis study aims to compare improvements in Attention Deficit and Hyperactivity Disorder (ADHD) symptom severity between a group of ADHD children and parents undergoing a new therapeutic program based on third generation cognitive-behavioural therapy (Hyper-mCBT) and a similar group undergoing treatment-as-usual with the Barkley program.Methods248 children diagnosed with ADHD will be randomly assigned to either a Hyper-mCBT program or a Barkley program. This is a randomized (1:1), 2 parallel-group, superiority trial with evaluator blinding and stratification according to center and methylphenidate treatment. Hyper-mCBT program consists in a series of 16 simultaneous-but-separate therapies sessions for parents and for children.DiscussionMore effective psychotherapeutic approaches are needed for ADHD children. Pharmacotherapy seems to be more effective in reducing ADHD symptoms but it is not always helpful, carries side effects and it is rejected by many parents/professionals. Results for psychotherapy programs for ADHD are inconsistent although several studies have shown clinical improvements. This trial will substantiate encouraging preliminary results of an innovative psychotherapy program for both parents and children.Trial registration: Sponsor Number: PHRC-N/2016/JLC-01RCB Identification: 2017-A01349-44 Clinicaltrials.gov registration: NCT03437772 (first posted: February 19, 2018)