Positioning value of objective analysis of macular ganglion cell complex (mGCC) in optic pathway-related neuro-ophthalmology

AbstractBackground: This study aimed to explore the positioning value of objective analysis of macular ganglion cell complex (mGCC) in optic pathway-related neuro-ophthalmology diseases. Methods: This retrospective study included 32 patients with optic pathway-related neuro-ophthalmology diseases. A swept-source optical coherence tomography (SS-OCT) was used to scan and analyze the morphological characteristics of mGCC thickness and peripapillary retinal nerve fiber layer (pRNFL) thickness in these patients, and then they were compared with the visual field changes at the corresponding phase to analyze their relationship. Results: In optic pathway-related neuro-ophthalmologic diseases, the morphological characteristics of mGCC thickness demonstrated similar characteristic changes to that of visual field, and mGCC analysis remained to be objective. Conclusion: The application of SS-OCT to examine the morphological changes of mGCC thickness has position value of objective analysis in the diagnosis and treatment of optic pathway-related neuro-ophthalmologic diseases.