Prenatal Diagnosis of Crossed Pulmonary Arteries with a Postnatal Diagnosis of CHARGE syndrome

Crossed pulmonary arteries (CPA) is a rare abnormality in which the ostium of the left pulmonary artery is located rightward and the ostium of the right pulmonary artery is leftward. CPA has been reported only once at prenatal period and has not been associated with CHARGE syndrome as yet. Prenatally left pulmonary artery was seen to pass beneath the ductus and directing towards the left side and pulmonary artery bifurcation could not be demonstrated at the same plane. Postnatal echocardiography reconfirmed the presence of CPA. Bilateral choanal atresia, genital hypoplasia, hearing loss with facial and external ear asymmetry and psychomotor retardation of the newborn led to clinical diagnosis of CHARGE syndrome and was confirmed by gene analysis.