Efficacy of 3 treatments for cervical endometriosis: clinical analysis of 106 cases

Objective To evaluate the clinical efficacy of 3 treatments for cervical endometriosis. Methods Clinical data of 106 patients with cervical endometriosis treated in our center from January 2013 to March 2019 were collected and retrospectively analyzed. According to the treatments, they were assigned into yttrium aluminum garnet (YAG) laser group (n=44, laser group), transvaginal administration of policresulen suppositories group (n=37, medication group) and YAG laser along with oral contraceptive group (n=25, Diane-35, combination group). The clinical efficacy and adverse effects were evaluated and compared among the 3 groups during the 6~12 months' follow-up. Results ① The total effective rates were 93.18% (41/44), 78.38% (29/37) and 96.00% (24/25), respectively, in the laser, medication and combination groups, with statistical difference among them (Chi-square=6.076, P 0.05) and the combination group (Chi-square=-1.239, P>0.05). In the medication group, the patients with lesions involving ≤2 quadrants had a higher recovery rate than those with >2 quadrants (Chi-square=-2.796, P < 0.01). ③ In the laser group, the recovery rate of the patients with simple cervical endometriosis was higher than that of those with other parts of endometriosis (Z=-2.124, P 0.05) and combination groups (Z=-0.873, P>0.05). ④ During the follow-up of 6~12 months, no recurrence was found in the combination group. The size of original lesion and involvement of other parts had no effect on the recurrence rate in the laser group (P>0.05). In the medication group, the patients with lesions of >2 quadrants or with other parts of endometriosis had higher recurrence rate (P < 0.05). Conclusion Size of cervical lesions and whether involved with other parts of endometriosis should be considered when choosing different treatment methods for cervical endometriosis.