Heterologous malignant mixed Müllerian tumor of the cervical stump

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⚙ AI-generated summary by qwen3.7-flash, 2026-10-14 ⓘ

This case report documents the first malignant mixed Müllerian tumor arising in a cervical stump, suggesting its development parallels endometrial neoplastic potential due to developmental kinship and noting a possible derivation from endometriosis.

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Abstract

A 76-year-old woman presented with vaginal bleeding 37 years following supracervical hysterectomy for a benign disease. Extensive malignant mixed Müllerian tumor was found in the remaining uterine cervix. This appears to be the first documented case of the malignant mixed Müllerian tumor arising in a cervical stump. Possibility of derivation of this tumor from endometriosis notwithstanding, the cervical Müllerian neoplastic potential parallels that of the endometrium because of the developmental kinship of the two. This potential has been fully retained and expressed as a tumor in the cervical stump in this case.

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MeSH descriptors

Neoplasms, Germ Cell and Embryonal Uterine Cervical Neoplasms Aged Aged Female Female Humans Humans Hysterectomy Hysterectomy Leiomyoma Leiomyoma Leiomyoma Neoplasms, Germ Cell and Embryonal Neoplasms, Germ Cell and Embryonal Neoplasms, Germ Cell and Embryonal Time Factors Time Factors Uterine Cervical Neoplasms Uterine Cervical Neoplasms

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Source provenance

europepmc
last seen: 2026-11-06T06:14:58.568748+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-10-08T21:58:08.863946+00:00
License: CC0 · commercial use OK