Clinical studies on therapeutic effectiveness on endometrioma by medroxyprogesterone after TCRE

Objective To evaluate the curative effects of medroxyprogesterone after transcervical resection of endometrium(TCRE).Methods Fifty cases with endometrioma were selected and randomly divided into two groups.Group A (n=25) were treated with medroxyprogesterone after TCRE yet Group B(n=25) were not treated with medroxyprogesterone.Sign and symptom remission rate after 6 months ,recurrent rates and CA125 were analyzed 12 months after surgery respectively.Reslts The amenorrhea rates of group A were significant higher than group B(P0.05).Sign and symptom remission rate of group A were significantly higher (P0.05).The one year recurrent rates of Group A were significant lower(P0.01).The level of alanine aminotransferase (ALT) increased in 2 of the 47 cases.11of the 47 cases had nausea or vomiting.Conclusions The method of using medroxyprogesterone after TCRE can reduce recurrent rates ,works effectively and should be popularized.