The Significant Contribution of Pasteur Institute of Iran to COVID-19 Pandemic Control: A Successful Map over the Obstacles

Abstract Background The present study aims to show the comprehensive effort of Pasteur Institute of Iran and its scientists regarding COVID-19 chaos management, related studies, achievements and vaccine production though there were many imposed challenges. Methods The relevant literature review was done through the associated data from national and international databases, published and under review research articles and also through reports obtained from official meetings with the heads of the related departments. Results The taken strategy adopted by Pasteur Institute of Iran was based on six arms including COVID-19 laboratory network establishment, vaccine research and production, monitoring of SARS-CoV-2 variants, diagnostic tests production, conduction of applied and basic research, and community management and support which eventually utilized appropriate technology for facilitating vaccination as well as the pandemic control at the right time. Conclusion The COVID-19 pandemic which was going to be a real crisis, led to a precise and great performance of Pasteur Institute of Iran owing to the unity of the scientists and the staff. COVID-19 pandemic has been managed by COVID-19 laboratory network set up, approved vaccines in collaboration with Cuba, evaluation and validation system of diagnostic and immunological COVID-19 kits, community Support and careful SARS-CoV-2 Variants Screening. COVID-19 is not over yet and the role of Pasteur Institute of Iran in dealing with this pandemic is still pivotal. There are some other challenges to overcome such as preparation for any COVID-19 probable trend, data management and update, long-term safety and efficacy of the vaccines and providing supplies.