Effect of combined mifepristone and surgery on pelvic endometriosis

Objective: To observe the effect of combined mifepristone and surgery on pelvic endometriosis.Methods: A total of 57 cases with pelvic endometriosis were randomly divided into two groups.30 cases in observation group were treated by mifepristone for 3 months from the 3rd day after surgery,one time per day,12.5 mg per time.While patients in control group didn′t have mifepristone.The effect was observed and compared.Results: The follow up for 3-12 months showed remission rate in observation group(53.3%) was significantly higher than that in control group(48.1%)(P0.05),and the recurrence rate in observation group was significantly lower(10.0% vs.18.5%)(P0.05).The incidence of side effect was 10.0% in observation group. Conclusions: Combined mifepristone and surgery is more effective on pelvic endometriosis than single surgery.Mifepristone is of little side effect and cheap.And it can be satisfactory option for treatment of pelvic endometriosis.