Sex steroid receptors expression in ectopic endometrium in women with different forms of endometriosis

Sex steroid receptors expression in ectopic endometrium in women with different forms of endometriosis DOI: https://doi.org/10.18370/2309-4117.2015.21.47-49Keywords: ectopic endometrium, endometriosis, receptors expression, progesterone receptors, estradiol receptorsAbstract Expression of antigens to estradiol and progesterone in the heterotopic endometrium was studied in order to determine the degree of hormone dependent of endometriosi various localization. Histological examination of extirpation uterus was conducted in 35 women of first groups with internal endometriosis, the second group consisted of 52 patients with external endometriosis and the third group consisted of 19 patients whom extragenital endometriosis, which was performed resection of endometriosis lesions. The obtained results showed significant reduction in the prevalence of estradiol and progesterone receptors expression in women of the first and the second groups unlike the third group. The degree of intensity of estradiol and progesterone receptors expression significantly decreased with distance of endometriosis lesions from uterus. References - Vovk, I.B., Zakharenko, N.F., Radysh, T.V. “Activation status of blood lymphocytes and serum levels of inflammatory mediators in various forms of endometriosis.” Pediatrics, Obstetrics and Gynecology, 1(76) (2013): 77–81. - Zakharenko, N.F., Zadorozhnia, T.D., Kalugina, L.V. “Indole-3-carbinol in the treatment of adenomyosis.” Ukrainian medicament plus, 2(15) (2013): 22–24. - Kosei, N.V., Zakharenko, N.F., Kovbasii, V.P. “Features of local hormonal homeostasis in women of childbearing age with uterus hyperproliferative diseases.” Women Health, 1(2013): 145–149. - A damson, D.G., Kennedy S., Hummelshoj, L. “Creating solutions in endometriosis:global collaboration through the World Endometriosis Research Foundation.” J Endometriosis, 2(2010): 3–6. - Strowitzki, T., Marr, J., Gerlinger, C., Faustmann, T., Seitz, C. “Dienogest is as effective as leuprolide acetate in treating the painful symptoms of endometriosis: a 24-week, randomized, multicentre, open-label trial.” Hum Reprod, 25(2010): 633–641. - Stilley, J.A., Birt, J.A., Sharpe-Timms, K.L. “Cellular and molecular basis for endometriosis-associated infertility.” Cell Tissue Res, 3(349) (2012): 849–862. Downloads Published How to Cite Issue Section License Copyright (c) 2015 Н. Ф. Захаренко This work is licensed under a Creative Commons Attribution 4.0 International License. Authors who publish with this journal agree to the following terms: - Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. - Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.