The Top 100 Most Cited Articles on Intrauterine Adhesion: A Bibliometric Analysis

The Top 100 Most Cited Articles on Intrauterine Adhesion: A Bibliometric Analysis | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Help Center Sign In Submit a Preprint Cite Share Download PDF Research The Top 100 Most Cited Articles on Intrauterine Adhesion: A Bibliometric Analysis Pan Gu, Waixing Li, Dabao Xu This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-345211/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 15 Nov, 2021 Read the published version in Reproductive Sciences → Version 1 posted You are reading this latest preprint version Abstract Background : Bibliometric analysis is a statistical method which attempts to assess articles by their citations, analyzing their frequency and pattern of citing phenomenon. Through the analysis, some guidance can be extracted for future research directions. Over the past few years, there have been articles published in mounting numbers focused on intrauterine adhesions. Nevertheless, little is known about the properties and qualities of these researches. No existed analysis commits to reflecting the progress of researches in intrauterine adhesion. Methods : Web of Science Core Collection, BIOSIS Citation Index and MEDLINE were searched for the identifying articles released from 1950 to October 2020. Articles concerning about Intrauterine adhesion were determined. Subsequently, the 100 most cited articles were chosen for analysis of citation count, citation density (citations/article age), authorship, theme, geographic distribution, time-related flux, level of evidence, and network analysis. Results : An overwhelming majority of the certain 100 articles were put out in the 2010s (35%). Citations per article ranged from 30 to 253. China possesses the most papers among the top 100 papers, followed by the USA, France, Israel and Italy. The study theme that most highlighted were operative hysteroscopy and adjunctive treatments for improving reproductive outcome. Level II is the most common level of evidence, and there is no statistical difference in the number of citations between the levels. The network analysis connoted that hysteroscopy, hysteroscopic adhesiolysis, infertility, and reproductive outcome had a great degree of centrality in the 2000s and 2010s, while placental implantation had a great degree of centrality in the 2000s and stem cell and fibrosis had a great degree of centrality in the 2010s. Conclusions : We conducted a bibliometric analysis of the top 100 most cited articles in the literature on intrauterine adhesions. It is worth noting that hysteroscopy and hysteroscopic adhesiolysis were long-term concern in the field of intrauterine adhesion researches. As the elapse of time, postoperative adjuvant treatment has gradually become the hot spot of researches. However, there are only 9 experimental articles among these 100 articles, showing the lack of breakthrough progress in the field of intrauterine adhesions at the mechanism level. Sexual & Reproductive Medicine Intrauterine adhesion hysteroscopy hysteroscopic adhesiolysis bibliometric analysis Figures Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Background Intrauterine adhesion (IUA) was first defined and reported by Asheman Joseph G in 1950 ( 1 , 2 ). IUA is caused by mechanical injury or infection hurt to the basal layer of the endometrium, resulting in the formation of fibromuscular or severe connective tissue adhesion of the uterine cavity or cervical canal ( 3 , 4 ). Hypomenorrhea/ amenorrhea ( 5 ), infertility( 6 ), recurrent pregnancy loss ( 7 ) and obstetric complications ( 8 ) are common complication of IUA. IUA may also lead to low birth weight ( 9 ). At present, IUA have become one of the stubborn diseases that seriously affect the reproductive prognosis and quality of lives of women in childbearing age ( 6 , 10 ). Surgical treatment is the first choice for IUA. Hysteroscopic adhesiolysis, the standard treatment for IUA, hold the limited therapeutic effect though ( 11 ). The conception rate is 25% after hysteroscopic adhesiolysis, and the rate of reformation of adhesions is 20%-63% ( 12 – 15 ). In order to reduce the recurrence rate of IUA and improve reproductive prognosis, it is often recommended to assist other prevention and treatment measures for comprehensive management of adhesions after the surgery ( 16 – 18 ). These measures mainly include devices to keep opposing endometrial surfaces separated, such as intrauterine device (IUD) ( 19 ), Foley catheter balloon ( 20 ), auto-crosslinked hyaluronic acid (ACP) gel ( 21 – 24 ), and interventions to promote endometrial regeneration, such as estrogen ( 25 , 26 ), stem cell ( 27 – 29 ), stem cell exosome ( 30 ), amniotic epithelial cells ( 31 ), granulocyte colony stimulating factor ( 32 ), platelet rich plasma ( 33 ), aspirin ( 34 ), etc. However, current effectiveness is still not ideally. The reformation rate is still as high as 48% ( 35 ), the conception rate is about 44.3%, and the live birth rate is 37.8% ( 36 ). Therefore, when it comes to IUA, how to reduce the reformation rate of IUA and increase the postoperative conception rate and live birth rate is still the main focus of research. The aim of this research is to figure out and analyze the 100 most cited essays in the field of IUA, emphasize the research trends and hotspots in this area, and evaluate the research quality and properties of the most cited original papers in the past 70 years. This analysis are supposed to provide some guidance for subsequent research directions. Methods Search strategy All articles were selected by searching the Web of Science Core Collection, BIOSIS Citation Index and MEDLINE to retrieve all articles which have relation to IUA. Searching process was done by two individuals at the same time to upgrade the search sensitivity. The terms used for searching were as follows: “Intrauterine adhesion” OR “Asherman Syndrome”. The exploring was conducted in October 2020 and yielded a total of 1,999 results. Subsequently, search results were filtered. Only original articles were included. Hence, articles in types of review articles, systematic reviews, meta-analyses, and guidelines were all excluded. In order to the number of screening articles, those articles which were cited less than 10 times were excluded. As a result, 418 articles were included for analysis. Two independent individuals reviewed the title and the abstract of all included articles. Articles that met the following criteria were included: ( 1 ) basic study, animal study, and clinical trials related to any aspect of IUA; ( 2 ) the clinical therapeutic, prognostic, diagnostic, epidemiological studies of IUA; ( 3 ) the case report data of IUA. Disagreement between the two reviewers was discussed to reach an agreement. After the title and abstract review, there were 241 articles remaining. These articles were ranked in descending order of citations and the first 100 most cited articles were included in this analysis (Fig. 1 ). Data extraction All articles were reviewed by two independent well-trained individuals. The following information was listed for all articles: the journal name, publication date, first author, year of publication, geographic origin, total number of citations of the article, overall citation rate (total citations/article age), research theme, and level of evidence (methodology has been described elsewhere( 37 )). Statistical analysis The Shapiro-Wilk test was used to test the distribution of individual variables for normality. Normally distributed data are presented as mean ± standard deviation. Comparison between means was performed using one way analysis of variance (ANOVA), and post-hoc testing was undertaken when necessary. Time-dependent trends were tested using the Mann-Kendall trend test. Correlation between variables was performed using the Spearman rank or Pearson tests. A P < 0.05 was considered to be statistically significant. Analysis was performed using IBM SPSS Statistics, Version 20.0. The Ucinet for windows, version 6.212 was used to perform the degree of centrality analysis( 38 ). Results We extracted 100 articles which is cited most in the field of IUA which is listed in Table 1. Citations ranges from 30 to 253 in number, with a majority of them published in the 2010s (35％) and 2000s (29％). The overall trend was increasing year by year (Fig. 2). In 2008, the number of journals reached highest (n=7). The number of citations was 6462 generally, 47 (0.7%) in the 1960s, 356 (5.5%) in the 1970s, 721 (11.2%) in the 1980s, 1190 (18.4%) in the 1990s, 2097 (32.5%) in the 2000s, and 2051 (31.7%) in the 2010s. The Mann-Kendall trend test showed no time-dependent trend in the publication time of articles (P=0.4654) but an increasing trend between the citation density and the time (P=2.2E-16) (Fig. 3). The Spearman rank revealed a positive correlation between time and citation density (r=0.836, P <2.2E-16). The Shapiro-Wilk test and the Kolmogorov-Smirnov test both indicated an abnormal distribution of the citation data. The Shapiro-Wilk test indicated significant departures from normality (p<0.05) for all distributions tested. Tab. 1 List of the 100 top-cited articles in intrauterine adhesion research Rank Publication year Total citation Title PMCID 1 1996 253 Frequency of factors associated with habitual abortion in 197 couples 8752606 2 2000 236 Diagnostic accuracy at sonohysterography, transvaginal sonography, and hysterosalpingography in patients with uterine cavity diseases 10685551 3 1988 204 Intrauterine adhesions: hysteroscopic diagnosis, classification, treatment, and reproductive outcome 3381869 4 2004 137 Effectiveness of auto-crosslinked hyaluronic acid gel in the prevention of intrauterine adhesions after hysteroscopic surgery: a prospective, randomized, controlled study 15105384 5 1978 133 Hysteroscopic management of intrauterine adhesions 637078 6 2003 129 Effectiveness of auto-cross-linked hyaluronic acid gel in the prevention of intrauterine adhesions after hysteroscopic adhesiolysis: a prospective, randomized, controlled study 12923149 7 2016 119 Autologous cell therapy with CD133+bone marrow-derived stem cells for refractory Asherman's syndrome and endometrial atrophy: a pilot cohort study 27005892 8 2011 117 Endometrial regeneration using autologous adult stem cells followed by conception by in vitro fertilization in a patient of severe Asherman's syndrome 21772740 9 2003 114 A comparison of two adjunctive treatments for intrauterine adhesions following lysis 12834941 10 2014 114 Bone Marrow-Derived Stem Cell (BMDSC) Transplantation Improves Fertility in a Murine Model of Asherman's Syndrome 24819371 11 2008 108 Factors affecting reproductive outcome of hysteroscopic adhesiolysis for Asherman's syndrome 17681324 12 1999 102 Hysteroscopic treatment of severe Asherman's syndrome and subsequent fertility 10325268 13 2004 99 1000 office-based hysteroscopies prior to in vitro fertilization: feasibility and findings 15119651 14 2010 97 Reproductive outcome following hysteroscopic adhesiolysis in patients with infertility due to Asherman's syndrome 19455349 15 1998 94 Prevalence of Asherman's syndrome after secondary removal of placental remnants or a repeat curettage for incomplete abortion 9886512 16 2012 93 Comprehensive management of severe Asherman syndrome and amenorrhea 22100167 17 1978 91 Diagnostic and therapeutic hysteroscopy for traumatic intrauterine adhesions 677196 18 1993 90 Incidence of post-abortion intra-uterine adhesions evaluated by hysteroscopy--a prospective study 8473464 19 1997 89 Hysteroscopic treatment of intrauterine adhesions is safe and effective in the restoration of normal menstruation and fertility 9418714 20 2008 87 Postoperative adhesiolysis therapy for intrauterine adhesions (Asherman's syndrome) 18571166 21 2010 84 Prevalence of unsuspected uterine cavity abnormalities diagnosed by office hysteroscopy prior to in vitro fertilization 20570971 22 1980 82 Hysteroscopy in the evaluation of female infertility 7386525 23 2006 82 Amnion graft following hysteroscopic lysis of intrauterine adhesions 17100817 24 2006 78 Fertility after treatment of Asherman's syndrome stage 3 and 4 16962521 25 2013 77 A comparison of intrauterine balloon, intrauterine contraceptive device and hyaluronic acid gel in the prevention of adhesion reformation following hysteroscopic surgery for Asherman syndrome: a cohort study 23932377 26 2010 75 Human Amnion as a Temporary Biologic Barrier after Hysteroscopic Lysis of Severe Intrauterine Adhesions: Pilot Study 20576472 27 1995 73 Reproductive outcome following hysteroscopic management of intrauterine septum and adhesions 8567788 28 2004 72 Live delivery rates in subfertile women with Asherman's syndrome after hysteroscopic adhesiolysis using the resectoscope or the Versapoint system 15169591 29 2011 72 Hysteroscopic Management of Residual Trophoblastic Tissue Is Superior to Ultrasound-Guided Curettage 22024264 30 2000 71 Predictive value of transvaginal sonography performed before routine diagnostic hysteroscopy for evaluation of infertility 10685552 31 2006 69 Reduction of postoperative adhesions with an auto-crosslinked hyaluronan gel in gynaecological laparoscopic surgery: a blinded, controlled, randomized, multicentre study 16439505 32 1986 68 Severe obstetric complications after aggressive treatment of Asherman syndrome 3703411 33 2013 68 Optimal waiting period for subsequent fertility treatment after various hysteroscopic surgeries 23433831 34 2014 66 Etiology, treatment, and reproductive prognosis of women with moderate-to-severe intrauterine adhesions 24598346 35 2015 66 Human CD133(+) bone marrow-derived stem cells promote endometrial proliferation in a murine model of Asherman syndrome 26384164 36 2009 65 Uterine synechiae after bipolar hysteroscopic resection of submucosal myomas in patients with infertility 18937941 37 2008 64 Efficiency and pregnancy outcome of serial intrauterine device-guided hysteroscopic adhesiolysis of intrauterine synechiae 18774563 38 2010 64 Fertility and pregnancy following pelvic arterial embolisation for postpartum haemorrhage 19832826 39 2003 63 A prospective comparative study between hysterosalpingography and hysteroscopy in the detection of intrauterine pathology in patients with infertility 12696625 40 2004 62 Diagnostic value of hysterosalpingography in the detection of intrauterine abnormalities: A comparison with hysteroscopy 15505312 41 2016 60 Autologous menstrual blood-derived stromal cells transplantation for severe Asherman's syndrome 27664218 42 1981 58 Gestational outcome following hysteroscopic lysis of adhesions 6269905 43 1988 58 Endometrial abnormalities: evaluation with transvaginal sonography 3275446 44 2008 58 Office hysteroscopic early lysis of intrauterine adhesion after transcervical resection of multiple apposing submucous myomas 17686478 45 2013 57 Role of angiogenesis in endometrial repair of patients with severe intrauterine adhesion 23826415 46 2014 57 Effect of stem cell application on Asherman syndrome, an experimental rat model 24974357 47 2007 56 Genital tuberculosis in Indian infertility patients 17362955 48 1984 54 Comparison of diagnostic accuracy of laparoscopy, hysteroscopy, and hysterosalpingography in evaluation of female infertility 6232154 49 1999 54 Transvaginal sonohysterographic evaluation of intrauterine adhesions 10064410 50 2012 52 The effect of collagen-binding vascular endothelial growth factor on the remodeling of scarred rat uterus following full-thickness injury 22136717 51 2007 51 Intrauterine adhesions as a risk factor for failed first-trimester pregnancy termination 17900447 52 2006 50 Successful use of vaginal sildenafil citrate in two infertility patients with Asherman's syndrome 16724891 53 1976 49 Obstetric complications after treatment of intrauterine synechiae (Asherman's syndrome) 934560 54 2011 49 Efficacy of a Polyethylene Oxide-Sodium Carboxymethylcellulose Gel in Prevention of Intrauterine Adhesions After Hysteroscopic Surgery 21777835 55 1979 48 Hysteroscopy in 100 patients 437163 56 2015 48 Randomized, controlled trial comparing the efficacy of intrauterine balloon and intrauterine contraceptive device in the prevention of adhesion reformation after hysteroscopic adhesiolysis 25936237 57 1966 47 The pathology of postcurettage intrauterine adhesions 5928449 58 1998 47 Myometrial scoring: a new technique for the management of severe Asherman's syndrome 9591493 59 2004 47 Hysteroscopy in the evaluation of patients with recurrent pregnancy loss - A cohort study in a primary care population 15809790 60 2016 47 MicroRNA-29b Inhibits Endometrial Fibrosis by Regulating the Sp1-TGF-beta 1/Smad-CTGF Axis in a Rat Model 26392347 61 1981 45 Significance of intrauterine adhesions detected hysteroscopically in eumenorrheic infertile women and role of antecedent curettage in their formation 7468688 62 1985 45 Etiology of cervical pregnancy. Association with abortion, pelvic pathology, IUDs and Asherman's syndrome 4038744 63 2008 44 Placenta Accreta An Association With Fibroids and Asherman Syndrome 18946102 64 2014 44 Does cold loop hysteroscopic myomectomy reduce intrauterine adhesions? A retrospective study 24182410 65 2011 43 Outpatient hysteroscopy: a routine investigation before assisted reproductive techniques? 20638055 66 2013 43 Creation of a female rabbit model for intrauterine adhesions using mechanical and infectious injury 23199550 67 2012 42 Changes in endometrial receptivity in women with Asherman's syndrome undergoing hysteroscopic adhesiolysis 22535194 68 1994 41 Post-abortion-hysteroscopy--a method for early diagnosis of congenital and acquired intrauterine causes of abortions 7713291 69 2015 41 Results of centralized Asherman surgery, 2003-2013 26428306 70 1992 40 Hysteroscopic findings after missed abortion 1521644 71 1993 40 Induced regeneration of endometrium following curettage for abortion: a comparative study 8408501 72 2007 40 Fluoroscopically guided synechiolysis for patients with Asherman's syndrome: menstrual and fertility outcomes 17109860 73 1997 39 Successful treatment of severe uterine synechiae with transcervical resectoscopy combined with laminaria tent 9194644 74 2005 39 Pathologic findings in hysteroscopy before in vitro fertilization-embryo transfer (IVF-ET) 16316847 75 2014 39 Diagnostic accuracy of three-dimensional sonohysterography compared with office hysteroscopy and its interrater/intrarater agreement in uterine cavity assessment after hysteroscopic metroplasty 24581576 76 1989 38 Value of intrauterine device insertion and estrogen administration after hysteroscopic metroplasty 2549238 77 2008 38 Thin unresponsive endometrium-a possible complication of surgical curettage compromising ART outcome 18797990 78 1983 37 Diagnosis and treatment of intrauterine adhesions by microhysteroscopy 6825866 79 2017 37 Prevalence of intrauterine adhesions after the application of hyaluronic acid gel after dilatation and curettage in women with at least one previous curettage: short-term outcomes of a multicenter, prospective randomized controlled trial 28390688 80 2018 37 Allogeneic cell therapy using umbilical cord MSCs on collagen scaffolds for patients with recurrent uterine adhesion: a phase I clinical trial 29996892 81 2010 36 Results of 2500 office-based diagnostic hysteroscopies before IVF 20207586 82 2017 36 Reproductive Outcomes in Patients With Intrauterine Adhesions Following Hysteroscopic Adhesiolysis: Experience From the Largest Women's Hospital in China 27856386 83 2017 36 Effects of Aspirin and Intrauterine Balloon on Endometrial Repair and Reproductive Prognosis in Patients with Severe Intrauterine Adhesion: A Prospective Cohort Study 28251159 84 1976 35 Intrauterine adhesions secondary to elective abortion. Hysteroscopic diagnosis and management 85 1992 35 Diagnostic hysteroscopy: its value in an in-vitro fertilization/embryo transfer unit 1291572 86 1996 35 Hysteroscopic management of uterine synechiae: a series of 102 observations 8730623 87 1999 35 Fluoroscopically guided hysteroscopic division of adhesions in severe Asherman syndrome 10362178 88 2000 35 Operative hysteroscopy for infertility using normal saline solution and a coaxial bipolar electrode: a pilot study 10920101 89 2007 35 Prevalence of uterine synechia after abortion evacuation curettage 18094891 90 2008 35 Genital tuberculosis: an important cause of Asherman's syndrome in India 17653564 91 2016 35 Endometrial stem cells repair injured endometrium and induce angiogenesis via AKT and ERK pathways 27486270 92 2015 34 Preventive effect of oral mucosal epithelial cell sheets on intrauterine adhesions 25475585 93 2007 33 Hysteroscopy after uterine fibroid embolization in women of fertile age 17578361 94 2016 33 The influence of the location and extent of intrauterine adhesions on recurrence after hysteroscopic adhesiolysis 25753391 95 2017 33 Human amniotic mesenchymal stromal cell transplantation improves endometrial regeneration in rodent models of intrauterine adhesions 28285950 96 1982 32 Asherman's syndrome. A comparison of therapeutic methods 7120210 97 1995 31 Preoperative sonographic measurement of endometrial pattern predicts outcome of surgical repair in patients with severe Asherman's syndrome 7843453 98 1996 31 Intrauterine adhesions: detection with transvaginal US 8638001 99 1999 31 Total corporal synechiae due to tuberculosis carry a very poor prognosis following hysteroscopic synechialysis 10438408 100 1997 30 Simplified therapy for Asherman's syndrome 9418695 These articles were distributed in 22 countries (Fig. 4), led by China (n=19) followed by the USA (n=18), France (n=8), Israel (n=8), and Italy (n=8). The allocation is presented on the world map (Fig. 5). In terms of regional distribution, most of the articles published from two countries: America and Asia. The rest were scattered in Europe, Africa and Oceania. Developed countries accounted for 67% of all countries mentioned above. Articles were all published in 33 journals, among which 27 articles were published in "Fertility and sterility", followed by "Human Reproduction" (n=16), American journal of obstetrics and gynecology" (n=6), "Journal of Minimally Invasive Gynecology" (n=5). (Table 2). Tab. 2 Journals of the 100 top-cited studies published. Publication Number account Total citation Average citation IF (2020) Fertility and sterility 27 1895 70 6.3 Human Reproduction 16 1171 73 5.7 American journal of obstetrics and gynecology 6 602 100 6.5 Journal of Minimally Invasive Gynecology 5 310 62 3.1 Obstetrics and Gynecology 4 187 47 5.5 Archives of Gynecology and Obstetrics 3 174 58 2.3 European journal of obstetrics, gynecology, and reproductive biology 3 153 51 1.9 International Journal of Gynecology & Obstetrics 3 236 79 2.2 Journal of Obstetrics and Gynaecology Research 3 178 59 1.4 The Journal of reproductive medicine 3 115 38 0.2 Bjog-an International Journal of Obstetrics and Gynaecology 2 97 49 4.7 Journal of Assisted Reproduction and Genetics 2 95 48 2.8 Reproductive Biomedicine Online 2 108 54 3.2 AJR. American journal of roentgenology 1 58 58 3.0 American Journal of Roentgenology 1 62 62 3.0 Biomaterials 1 52 52 10.3 Biomed Research International 1 36 36 2.3 Contraception 1 51 51 2.8 Cytotherapy 1 33 33 4.2 Gynecological Endocrinology 1 39 39 1.6 International Journal of Clinical and Experimental Pathology 1 57 57 0.3 Journal of human reproductive sciences 1 54 54 0.8 Journal of Clinical Ultrasound 1 117 117 1.0 Journal of Surgical Research 1 43 43 1.8 Journal of Ultrasound in Medicine 1 44 44 1.8 Journal of Womens Health 1 50 50 1.9 JSLS: Journal of the Society of Laparoendoscopic Surgeons 1 99 99 1.5 Plos One 1 114 114 2.7 Radiology 1 31 31 7.9 Reproduction 1 35 35 3.2 Reproductive Sciences 1 47 47 2.6 Sao Paulo Medical Journal 1 35 35 1.0 Stem Cell Research & Therapy 1 37 37 5.1 Surgical Endoscopy and Other Interventional Techniques 1 47 47 3.1 Among the 100 highly cited articles, 10 researchers have more than two articles which is listed in Table 3. These authors’ articles are all clinical studies related to IUA. Among them, CM March and Jehn-Hsiahn Yang had 3 fist authorships mainly in the field of IUA. CM March’s focus was on hysteroscopic adhesiolysis, and Jehn-Hsiahn Yang’s research direction was endometrium regeneration. Although R F Valle from the United States had only two articles, the number of citations is relatively high, with an overall number of citations of 286. Auxiliary diagnosis of IUA is his main focus. Tab. 3 List of first authors with frequent articles within the top-cited list. First Author Number of Study Citations Account Author’s Affiliation C M March 3 226 Department of Obstetrics and Gynecology, University of Southern California School of Medicine Los Angeles, California, USA. Jehn-Hsiahn Yang 3 159 Department of Obstetrics and Gynecology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. R F Valle 2 286 Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinios, USA Mohamed I Amer 2 157 Department of Obstetrics and Gynecology, Ain Shams University, Cairo, Egypt. Recai Pabuccu 2 153 Department of Obstetrics and Gynecology, Gülhane School of Medicine, Ankara, Turkey. Xiaona Lin 2 125 Center of Reproductive Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, PR China. H Fernandez 2 113 Department of Obstetrics and Gynaecology, Antoine Béclère Hospital, Clamart Cedex, France. Yuqing Chen 2 93 Department of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. P J Taylor 2 93 Department of Obstetrics and Gynecology, University of Calgary and Foothills Hospital, Calgary, Alberta, Canada A Golan 2 75 Department of Obstetrics and Gynecology, Assaf Harofeh Medical Center, Zerifin, Israel. The 100 most cited articles mainly focus on the following themes: auxiliary treatment of IUA (n = 28), prognosis of IUA (n=19), incentive factors of IUA (n=16), hysteroscopic adhesiolysis (n=14), evaluation methods for IUA (n=12), complications of IUA (n = 6), relevant mechanism of IUA (n = 4), new devices for IUA (n=1). The most mentioned theme was the adjuvant treatment of IUA, followed by the reproductive prognosis of patients after hysteroscopic adhesiolysis (Fig. 6). One-way ANOVA revealed no significant difference in citations per article among the various themes (Fig. 7). Nevertheless, the impact factor of article from different themes was statistically different (P=0.012) (Fig. 8). In terms of the level of article evidence, the level II (n=39) category has a mean number of 69 ± 48 citations per article, making up the largest number. The level I (n=23) category has a mean number of 63±30 citations per article, the level IV (n=14) with 48±22 citations. Difference in citations per article between different levels of evidence is not significant analyzed by one-way ANOVA (Fig. 9). Network analysis of the key words or subject terms has been done in two periods of article published time: in the 2000s (34 articles) and in the 2010s (30 articles). The result indicated that "hysteroscopy", "hysteroscopic adhesiolysis", "infertility", and "reproductive outcome" possessed a high degree of centrality in the 2000s and 2010s, while "placenta accrete" were greatly centralized in the 2000s and "stem cell" and "fibrosis" was highly concentrated in the 2010s (Fig. 10-11). Discussion This is the first bibliometric analysis of papers in the field of IUA. Mass of interesting findings can be drawn from this analysis of the top 100 most cited papers published on IUA in the past 70 years. Not only the papers which had made important contributions to the progress in this field were reflected, but also current development trend was revealed. Generally speaking, with the time goes by, the number of citations of papers would be piled up. However, it is contrary to expectation that the number of articles was gradually increasing as time progresses when we assessed the certain 100 most cited articles according to the division of each decade. Articles in 2010s possessed the highest proportion, reaching 35%. As time increases, not only the proportion of articles presented an growing trend, but also the citation density, that is, the number of citations divided by the number of years of publication, figured an increasing trend. On the one hand, this reflects the "obliteration by incorporation" ( 39 ), that is, the citations of the original work decreased with the passage of time for familiarity during the long-term and widespread use, and new findings replaced them. On the other hand, this also presented the phenomenon that the diagnosis, treatment and advanced researches related to IUA have been paid more and more attention by the international community. In addition, 91% of these articles were clinical studies, and only 9% were basic experimental studies. Those basic studies mentioned above were all published in the 2010s. We may say that clinical research has always been the focus of researchers in the field of IUA. However, the disease mechanism is also crucial to the treatment of the disease. Current researches on the mechanism had an increasing trend, and it has the potential to provide clinical directions in the future. Different from the trend of other bibliometric analysis reports, articles originating from the United States and developed countries did not have an absolute advantage. China and the United States were both important sources of articles, with 19 and 18 articles respectively. 33% of the 100 most cited papers were from developing countries, 67% were from developed countries. There are several reasons for this condition: ( 1 ) The clinical manifestations of IUA were first reported in the United States in the 19th century, and later defined and named by American doctors. Therefore, they were able to study it earlier and more systematically ( 40 );The United States and other developed countries had sufficient funds to support scientific research. The sharing of these research results will help the progress of researches on IUA ( 41 , 42 ); ( 2 ) As we all know, the occurrence of IUA is closely related to abortion and curettage. Honestly, abortion is considered illegal in many developing countries due to religious beliefs. In developed countries, the rate of abortion dropped by 19 percentage points from 1990 to 2014, while it only fell by 2 percentage points in developing countries ( 43 ). Moreover, least-safe abortions accounted for the largest proportion in developing countries ( 44 ); ( 3 ) China and other developing countries had great population. Propaganda and popularization of contraceptive measures were inadequate. It was inevitable to choose surgical abortion after unintended pregnancy. Repeated or informal intrauterine operations may finally lead to irreversible hurt to endometrium ( 45 , 46 ); ( 4 ) After China opened up the two-child policy, more and more IUA were discovered, and recurrent IUA need to be treated ( 47 , 48 ). IUA is a universal disease, but unfortunately, no multinational cooperation work was found in these 100 most cited papers. Actually, the impact factors of journals were not high. This was because related papers were rarely published in comprehensive journals, while the impact factors of obstetrics and gynecology professional journals are relatively low. This result highlighted a growing tendency that researchers may prefer to publish articles in influential professional journals. However, there was no denying that the value of IUA researches have not been highly appreciated. Nearly 50% of the certain 100 papers were issued in two journals, “Fertility and sterility” and “Human Reproduction”, followed closely by two heavyweight journals in the field of obstetrics and gynecology, “American journal of obstetrics and gynecology” and “Obstetrics and Gynecology”. This demonstrated that IUA were particularly concerned in the field of reproductive medicine. Among the 100 most cited articles, the themes of papers published in recent years appeared to be more diverse, including the Phase I clinical study of autologous stem cell transplantation for the treatment of IUA published in Stem Cell Research & Therapy ( 49 ), and collagen scaffold for endometrial regeneration published in Biomaterials ( 50 ). When it comes to the first author of the 100 most cited papers, we found that 2 researchers contributed 3 articles. One of them was Charles M. March from the United States. His articles were all published before 1990, and emphasized that hysteroscopy is the gold standard for diagnosis and classification of IUA, and hysteroscopic adhesiolysis is the first choice for the treatment of IUA ( 51 – 53 ). The other one was Jehn-Hsiahn Yang from Taiwan, China, a younger generation of researchers. The similarity with Charles M. March was that they both focus on hysteroscopy. His three articles have proposed that IUA was common complications after transcervical resection of multiple apposing submucous myomas ( 54 ), the formation of new adhesions after hysteroscopic adhesiolysis was the reason that affects endometrial repair ( 55 ), the location and area of adhesions were important factors that affect the recurrence of IUA ( 15 ). The level of evidence was between I and V. The overall distribution was average, and level II was relatively high, which is distinct with other bibliometric-related studies. This may attribute to the design of clinical trials. Treatment of IUA was closely related to patients’ reproductive prognosis, and for women, age was also a significant factor. Therefore, considering the effect of placebo control on patients, experimental studies are mostly unilateral. In the future, with the increase in the demand for childbirth and the introduction of two or even three-child opening policies in some countries, it is expected that hysteroscopic adhesiolysis, postoperative adjuvant treatment and related research articles will increase more rapidly. We also studied the theme distribution of articles. The adjuvant treatment of IUA ranked first, followed by the prognosis of reproductive outcome after hysteroscopic adhesiolysis, the incentive factors of IUA, hysteroscopic adhesiolysis and the evaluation method of IUA. Hysteroscopic adhesiolysis is the primary treatment method. However, how to improve the therapeutic effect through drugs and biological agents after the surgery has been a problem that researchers want to overcome in recent years ( 56 ). Network analysis of the author’s key words or subject terms has been done in two periods of article published time: in the 2000s (34 articles) and in the 2010s (30 articles). The result indicated that “"hysteroscopy, hysteroscopic adhesiolysis, infertility and reproductive outcome" was highly centralized in both 2000s and 2010s and placental implantation was highly concentrated in the 2000s. This was consistent with the research trend in recent years. Researchers have gradually realized that even if patients with IUA succeed in conception, there would be many risks of pregnancy complications. The most cited article in this study was also an article about IUA complications, in which the author proposed that patients with IUA were associated with many risks during pregnancy. An analysis of the citation density of papers published in the 2010s, we found each theme was evenly distributed. In the analysis of the impact factor under each theme, it could be seen that articles related to devices and materials were relatively high, while researches on mechanism were relatively low. Stem cell and fibrosis were highly concentrated in the 2010s. In recent years, researchers have paid more and more attention to the effectiveness of adjuvant therapy after hysteroscopic adhesiolysis in suppressing reformation of adhesion and promoting endometrial regeneration ( 57 ). Previous researches focused on placement of uterine stents, foley catheters, hyaluronic acid or hormone replacement therapy ( 58 ). Nevertheless, more importance was attached to biotherapy, especially in the field of stem cell therapy. Bone marrow mesenchymal stem cells (BMSC) ( 59 ), umbilical cord mesenchymal stem cells (UCMSC) ( 60 ), and menstrual blood mesenchymal stem cells (MbMSC) ( 61 , 62 ) have been used clinically in patients with IUA, resulting in an improvement in reproductive outcome. Researchers reported that the stem cells can promote endometrial cells proliferation, especially inhibit the process of fibrosis ( 63 ). In 2020, a review brought together the controversies of different researchers on the treatment of IUA ( 64 ). One believed that the adjuvant treatment after the surgery should be paid attention to, and another believed that IUA should be treated with multiple operations. However, it cannot be ignored that, hysteroscopic adhesiolysis has always been the center of research over the years, and the discussion of surgical methods and surgical techniques was still a vacancy ( 65 ) It is undeniable that the combined effective adjuvant treatment after surgery is the trend of IUA treatment. This analysis does generate some valuable information, but it still has some restrictions. First of all, the citation analysis was mainly based on Web of Science. The number of citations may be misleading. Meanwhile, we may miss some important papers that were not included in the SCI database. Secondly, we may overlook the newly published articles that were meaningful in this area but have yet to reach high citation levels owing to the criterion that papers were sorted by the number of citations. All in all, it was by no means exhaustive, but the list of most cited articles still includes many influential papers in the field of IUA. Conclusion This article highlights the top 100 most cited articles in the IUA over the last 70 years, including their publication time and regional centers, first author, level of evidence, as well as their research theme. We revealed the spotlights and properties of studies about IUA since 1950 to 2020. Furthermore, this article sheds light on the notion that postoperative adjuvant therapy played a key role in the field of IUA, and more and more basic and clinical studies are exploring suitable and effective adjuvant treatments for IUA. Meanwhile, the method and techniques of surgical therapy is also controversial. However, the current prognosis of IUA was extremely poor. The tough problem still remains to be solved. Researchers extremely focused on the clinical trial rather than the basic laboratory research. Thus, the foremost difficult is to conquer the situation that little is known about underlying mechanisms of adhesion formation in the uterine and influencing factors. Abbreviations IUA : intrauterine adhesion IUD : intrauterine device ACP : auto-crosslinked hyaluronic acid BMSC : bone marrow mesenchymal stem cells UCMSC : umbilical cord mesenchymal stem cells MbMSC : menstrual blood mesenchymal stem cells Declarations Ethics approval and consent to participate Not applicable Consent for publication Not applicable Availability of data and materials Not applicable Competing interests The authors declare that they have no competing interests. Funding This study was supported by the National Key Research and Development Program of China (grant no. 2018YFC1004800). Authors' contributions DX contributed to the design of the study and revise the manuscript. PG and WL contributed to the process of searching, selecting and drafting the manuscript. 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Consideration for an optimal and practical approach to hysteroscopic adhesiolysis of intrauterine adhesions. Ann Transl Med. 2020;8(11):663. Cite Share Download PDF Status: Published Journal Publication published 15 Nov, 2021 Read the published version in Reproductive Sciences → Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About In Review Editorial Policies Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-345211","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research","associatedPublications":[],"authors":[{"id":19867732,"identity":"4ffa8d45-d7af-49fb-a9b5-d55a6f3896c1","order_by":0,"name":"Pan Gu","email":"","orcid":"","institution":"Central South University","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Pan","middleName":"","lastName":"Gu","suffix":""},{"id":19867733,"identity":"70e7f50f-5d5a-4379-98f1-6e3982afcbac","order_by":1,"name":"Waixing Li","email":"","orcid":"","institution":"Central South University","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Waixing","middleName":"","lastName":"Li","suffix":""},{"id":19867734,"identity":"01f6fefd-e089-4aff-aaa9-34d288e882b8","order_by":2,"name":"Dabao Xu","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAAuElEQVRIiWNgGAWjYDCCAzxgSo6BgYdELcaka0lsIFoL3/GzBz98bDucvgHIePCBwU5Ot4GAFskzecmSM84czt0AZBjOYEg2NjtAQIvBgRwDaZ4KoJYDOWbSPAwHErcR1HL+jfFvHoPD6UAGsVpugAyvOJwAYRCjRfLGuzTLGWfSDWfeeGNsOMOACL/wnc89fONjm7U83/kcwwcfKuzkCGqBAwWwSgNilYOAfAMpqkfBKBgFo2BEAQCBiEb3gnmPlQAAAABJRU5ErkJggg==","orcid":"","institution":"Central South University Third Xiangya Hospital","correspondingAuthor":true,"submittingAuthor":false,"prefix":"","firstName":"Dabao","middleName":"","lastName":"Xu","suffix":""}],"badges":[],"createdAt":"2021-03-19 15:03:21","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-345211/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-345211/v1","draftVersion":[],"editorialEvents":[{"content":"https://doi.org/10.1007/s43032-021-00794-x","type":"published","date":"2021-11-15T16:42:44+00:00"}],"editorialNote":"","failedWorkflow":false,"files":[{"id":7716333,"identity":"9930bd63-ade9-4c32-a11b-3ad1c7f89b99","added_by":"auto","created_at":"2021-04-06 16:04:17","extension":"png","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":76036,"visible":true,"origin":"","legend":"Flowchart illustrating the process of allocation of articles","description":"","filename":"floatimage1.png","url":"https://assets-eu.researchsquare.com/files/rs-345211/v1/268cf8064a97a5d7d8c83869.png"},{"id":7716310,"identity":"685a610e-a47b-4e89-aeb4-3371a578605c","added_by":"auto","created_at":"2021-04-06 16:04:14","extension":"png","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":71603,"visible":true,"origin":"","legend":"Time distribution of 100 top-cited articles in intrauterine adhesion","description":"","filename":"floatimage2.png","url":"https://assets-eu.researchsquare.com/files/rs-345211/v1/7bdc45a6b1eca19d90961178.png"},{"id":7716315,"identity":"cf87da87-b8a1-4078-975a-52d276bea1ae","added_by":"auto","created_at":"2021-04-06 16:04:16","extension":"png","order_by":3,"title":"Figure 3","display":"","copyAsset":false,"role":"figure","size":19894,"visible":true,"origin":"","legend":"Time-dependent citation density trend of 100 top-cited articles in intrauterine adhesion","description":"","filename":"Onlinefloatimage3.png","url":"https://assets-eu.researchsquare.com/files/rs-345211/v1/132539f145483565c3a8ab57.png"},{"id":7716314,"identity":"0fdb1861-f201-4192-b61d-a76861a2c97e","added_by":"auto","created_at":"2021-04-06 16:04:15","extension":"png","order_by":4,"title":"Figure 4","display":"","copyAsset":false,"role":"figure","size":84666,"visible":true,"origin":"","legend":"Countries of 100 top-cited articles in intrauterine adhesion","description":"","filename":"floatimage4.png","url":"https://assets-eu.researchsquare.com/files/rs-345211/v1/d59e093009b1623ecbca5bbd.png"},{"id":7716790,"identity":"3a2ce3d6-fbab-442f-b36c-3d51b07e11d0","added_by":"auto","created_at":"2021-04-06 16:07:16","extension":"png","order_by":5,"title":"Figure 5","display":"","copyAsset":false,"role":"figure","size":155966,"visible":true,"origin":"","legend":"Geographical distribution of 100 top-cited articles in intrauterine adhesion\n\nNote: The designations employed and the presentation of the material on this map\ndo not imply the expression of any opinion whatsoever on the part of Research Square concerning\nthe legal status of any country, territory, city or area or of its authorities, \nor concerning the delimitation of its frontiers or boundaries. This map has been provided by the authors.","description":"","filename":"floatimage5.png","url":"https://assets-eu.researchsquare.com/files/rs-345211/v1/877ca173c192da55e683ab11.png"},{"id":7716336,"identity":"40e95321-1b40-4c3d-a479-475e1742be4a","added_by":"auto","created_at":"2021-04-06 16:04:18","extension":"png","order_by":6,"title":"Figure 6","display":"","copyAsset":false,"role":"figure","size":26451,"visible":true,"origin":"","legend":"The themes distribution of 100 top-cited articles in intrauterine adhesion","description":"","filename":"floatimage6.png","url":"https://assets-eu.researchsquare.com/files/rs-345211/v1/c148e23442ba9ac7303d40b2.png"},{"id":7716787,"identity":"4161d5e2-a16c-4e7a-807d-9ba4c4456be6","added_by":"auto","created_at":"2021-04-06 16:07:15","extension":"png","order_by":7,"title":"Figure 7","display":"","copyAsset":false,"role":"figure","size":33474,"visible":true,"origin":"","legend":"Mean citation per article based on theme","description":"","filename":"floatimage7.png","url":"https://assets-eu.researchsquare.com/files/rs-345211/v1/4f1789c396e9372d76a3ffc1.png"},{"id":7716319,"identity":"4c969225-89cb-499f-a590-2ec7a74d300d","added_by":"auto","created_at":"2021-04-06 16:04:16","extension":"jpeg","order_by":8,"title":"Figure 8","display":"","copyAsset":false,"role":"figure","size":122427,"visible":true,"origin":"","legend":"Mean impact factor per article based on theme","description":"","filename":"floatimage8.jpeg","url":"https://assets-eu.researchsquare.com/files/rs-345211/v1/cf9ea8d49abe596a67706e0c.jpeg"},{"id":7716788,"identity":"bc6ab184-3528-4e51-a7d2-2d507ec1d07b","added_by":"auto","created_at":"2021-04-06 16:07:15","extension":"png","order_by":9,"title":"Figure 9","display":"","copyAsset":false,"role":"figure","size":14546,"visible":true,"origin":"","legend":"Mean citation per article based on level of evidence","description":"","filename":"floatimage9.png","url":"https://assets-eu.researchsquare.com/files/rs-345211/v1/4a96953ac099cb61b2724ad8.png"},{"id":7716789,"identity":"9a0f3400-678d-43fb-9ad7-b642dcbd20dd","added_by":"auto","created_at":"2021-04-06 16:07:16","extension":"jpeg","order_by":10,"title":"Figure 10","display":"","copyAsset":false,"role":"figure","size":298304,"visible":true,"origin":"","legend":"Degree centrality analysis in the 2000s (34 articles)","description":"","filename":"floatimage10.jpeg","url":"https://assets-eu.researchsquare.com/files/rs-345211/v1/7a8ebd73aba1e7b883104c16.jpeg"},{"id":7716321,"identity":"ff2d8b7b-60f0-4962-8db1-16c7f88e2dd0","added_by":"auto","created_at":"2021-04-06 16:04:16","extension":"jpeg","order_by":11,"title":"Figure 11","display":"","copyAsset":false,"role":"figure","size":313749,"visible":true,"origin":"","legend":"Degree centrality analysis in the 2010s (30 articles)","description":"","filename":"floatimage11.jpeg","url":"https://assets-eu.researchsquare.com/files/rs-345211/v1/7450b2ce7f60ab6d7b3aad97.jpeg"},{"id":15555421,"identity":"24144760-0668-4c6c-8db5-090f2f5f6041","added_by":"auto","created_at":"2021-11-15 16:42:52","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":1089339,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-345211/v1/f4f79433-b781-4180-b5e7-a7356ab74411.pdf"}],"financialInterests":"","formattedTitle":"\u003cp\u003eThe Top 100 Most Cited Articles on Intrauterine Adhesion: A Bibliometric Analysis\u003c/p\u003e","fulltext":[{"header":"Background","content":" \u003cp\u003eIntrauterine adhesion (IUA) was first defined and reported by Asheman Joseph G in 1950 (\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e, \u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e). IUA is caused by mechanical injury or infection hurt to the basal layer of the endometrium, resulting in the formation of fibromuscular or severe connective tissue adhesion of the uterine cavity or cervical canal (\u003cspan citationid=\"CR3\" class=\"CitationRef\"\u003e3\u003c/span\u003e, \u003cspan citationid=\"CR4\" class=\"CitationRef\"\u003e4\u003c/span\u003e). Hypomenorrhea/ amenorrhea (\u003cspan citationid=\"CR5\" class=\"CitationRef\"\u003e5\u003c/span\u003e), infertility(\u003cspan citationid=\"CR6\" class=\"CitationRef\"\u003e6\u003c/span\u003e), recurrent pregnancy loss (\u003cspan citationid=\"CR7\" class=\"CitationRef\"\u003e7\u003c/span\u003e) and obstetric complications (\u003cspan citationid=\"CR8\" class=\"CitationRef\"\u003e8\u003c/span\u003e) are common complication of IUA. IUA may also lead to low birth weight (\u003cspan citationid=\"CR9\" class=\"CitationRef\"\u003e9\u003c/span\u003e). At present, IUA have become one of the stubborn diseases that seriously affect the reproductive prognosis and quality of lives of women in childbearing age (\u003cspan citationid=\"CR6\" class=\"CitationRef\"\u003e6\u003c/span\u003e, \u003cspan citationid=\"CR10\" class=\"CitationRef\"\u003e10\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eSurgical treatment is the first choice for IUA. Hysteroscopic adhesiolysis, the standard treatment for IUA, hold the limited therapeutic effect though (\u003cspan citationid=\"CR11\" class=\"CitationRef\"\u003e11\u003c/span\u003e). The conception rate is 25% after hysteroscopic adhesiolysis, and the rate of reformation of adhesions is 20%-63% (\u003cspan additionalcitationids=\"CR13 CR14\" citationid=\"CR12\" class=\"CitationRef\"\u003e12\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR15\" class=\"CitationRef\"\u003e15\u003c/span\u003e). In order to reduce the recurrence rate of IUA and improve reproductive prognosis, it is often recommended to assist other prevention and treatment measures for comprehensive management of adhesions after the surgery (\u003cspan additionalcitationids=\"CR17\" citationid=\"CR16\" class=\"CitationRef\"\u003e16\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR18\" class=\"CitationRef\"\u003e18\u003c/span\u003e). These measures mainly include devices to keep opposing endometrial surfaces separated, such as intrauterine device (IUD) (\u003cspan citationid=\"CR19\" class=\"CitationRef\"\u003e19\u003c/span\u003e), Foley catheter balloon (\u003cspan citationid=\"CR20\" class=\"CitationRef\"\u003e20\u003c/span\u003e), auto-crosslinked hyaluronic acid (ACP) gel (\u003cspan additionalcitationids=\"CR22 CR23\" citationid=\"CR21\" class=\"CitationRef\"\u003e21\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR24\" class=\"CitationRef\"\u003e24\u003c/span\u003e), and interventions to promote endometrial regeneration, such as estrogen (\u003cspan citationid=\"CR25\" class=\"CitationRef\"\u003e25\u003c/span\u003e, \u003cspan citationid=\"CR26\" class=\"CitationRef\"\u003e26\u003c/span\u003e), stem cell (\u003cspan additionalcitationids=\"CR28\" citationid=\"CR27\" class=\"CitationRef\"\u003e27\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR29\" class=\"CitationRef\"\u003e29\u003c/span\u003e), stem cell exosome (\u003cspan citationid=\"CR30\" class=\"CitationRef\"\u003e30\u003c/span\u003e), amniotic epithelial cells (\u003cspan citationid=\"CR31\" class=\"CitationRef\"\u003e31\u003c/span\u003e), granulocyte colony stimulating factor (\u003cspan citationid=\"CR32\" class=\"CitationRef\"\u003e32\u003c/span\u003e), platelet rich plasma (\u003cspan citationid=\"CR33\" class=\"CitationRef\"\u003e33\u003c/span\u003e), aspirin (\u003cspan citationid=\"CR34\" class=\"CitationRef\"\u003e34\u003c/span\u003e), etc. However, current effectiveness is still not ideally. The reformation rate is still as high as 48% (\u003cspan citationid=\"CR35\" class=\"CitationRef\"\u003e35\u003c/span\u003e), the conception rate is about 44.3%, and the live birth rate is 37.8% (\u003cspan citationid=\"CR36\" class=\"CitationRef\"\u003e36\u003c/span\u003e). Therefore, when it comes to IUA, how to reduce the reformation rate of IUA and increase the postoperative conception rate and live birth rate is still the main focus of research.\u003c/p\u003e \u003cp\u003eThe aim of this research is to figure out and analyze the 100 most cited essays in the field of IUA, emphasize the research trends and hotspots in this area, and evaluate the research quality and properties of the most cited original papers in the past 70 years. This analysis are supposed to provide some guidance for subsequent research directions.\u003c/p\u003e "},{"header":"Methods","content":" \u003cdiv id=\"Sec3\" class=\"Section2\"\u003e \u003ch2\u003eSearch strategy\u003c/h2\u003e \u003cp\u003eAll articles were selected by searching the Web of Science Core Collection, BIOSIS Citation Index and MEDLINE to retrieve all articles which have relation to IUA. Searching process was done by two individuals at the same time to upgrade the search sensitivity. The terms used for searching were as follows: \u0026ldquo;Intrauterine adhesion\u0026rdquo; OR \u0026ldquo;Asherman Syndrome\u0026rdquo;.\u003c/p\u003e \u003cp\u003eThe exploring was conducted in October 2020 and yielded a total of 1,999 results. Subsequently, search results were filtered. Only original articles were included. Hence, articles in types of review articles, systematic reviews, meta-analyses, and guidelines were all excluded. In order to the number of screening articles, those articles which were cited less than 10 times were excluded. As a result, 418 articles were included for analysis. Two independent individuals reviewed the title and the abstract of all included articles. Articles that met the following criteria were included: (\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e) basic study, animal study, and clinical trials related to any aspect of IUA; (\u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e) the clinical therapeutic, prognostic, diagnostic, epidemiological studies of IUA; (\u003cspan citationid=\"CR3\" class=\"CitationRef\"\u003e3\u003c/span\u003e) the case report data of IUA. Disagreement between the two reviewers was discussed to reach an agreement. After the title and abstract review, there were 241 articles remaining. These articles were ranked in descending order of citations and the first 100 most cited articles were included in this analysis (Fig.\u0026nbsp;\u003cspan refid=\"Fig1\" class=\"InternalRef\"\u003e1\u003c/span\u003e).\u003c/p\u003e \u003c/div\u003e \u003cdiv id=\"Sec4\" class=\"Section2\"\u003e \u003ch2\u003eData extraction\u003c/h2\u003e \u003cp\u003eAll articles were reviewed by two independent well-trained individuals. The following information was listed for all articles: the journal name, publication date, first author, year of publication, geographic origin, total number of citations of the article, overall citation rate (total citations/article age), research theme, and level of evidence (methodology has been described elsewhere(\u003cspan citationid=\"CR37\" class=\"CitationRef\"\u003e37\u003c/span\u003e)).\u003c/p\u003e \u003c/div\u003e \u003cdiv id=\"Sec5\" class=\"Section2\"\u003e \u003ch2\u003eStatistical analysis\u003c/h2\u003e \u003cp\u003eThe Shapiro-Wilk test was used to test the distribution of individual variables for normality. Normally distributed data are presented as mean\u0026thinsp;\u0026plusmn;\u0026thinsp;standard deviation. Comparison between means was performed using one way analysis of variance (ANOVA), and post-hoc testing was undertaken when necessary. Time-dependent trends were tested using the Mann-Kendall trend test. Correlation between variables was performed using the Spearman rank or Pearson tests. A P\u0026thinsp;\u0026lt;\u0026thinsp;0.05 was considered to be statistically significant. Analysis was performed using IBM SPSS Statistics, Version 20.0. The Ucinet for windows, version 6.212 was used to perform the degree of centrality analysis(\u003cspan citationid=\"CR38\" class=\"CitationRef\"\u003e38\u003c/span\u003e).\u003c/p\u003e \u003c/div\u003e "},{"header":"Results","content":"\u003cp\u003eWe extracted 100 articles which is cited most in the field of IUA which is listed in Table 1. Citations ranges from 30 to 253 in number, with a majority of them published in the 2010s (35％) and 2000s (29％). The overall trend was increasing year by year (Fig. 2). In 2008, the number of journals reached highest (n=7). The number of citations was 6462 generally, 47 (0.7%) in the 1960s, 356 (5.5%) in the 1970s, 721 (11.2%) in the 1980s, 1190 (18.4%) in the 1990s, 2097 (32.5%) in the 2000s, and 2051 (31.7%) in the 2010s. The Mann-Kendall trend test showed no time-dependent trend in the publication time of articles (P=0.4654) but an increasing trend between the citation density and the time (P=2.2E-16) (Fig. 3). The Spearman rank revealed a positive correlation between time and citation density (r=0.836, P \u0026lt;2.2E-16). The Shapiro-Wilk test and the Kolmogorov-Smirnov test both indicated an abnormal distribution of the citation data. The Shapiro-Wilk test indicated significant departures from normality (p\u0026lt;0.05) for all distributions tested.\u003c/p\u003e\n\u003cp style=\"text-align: center;\"\u003eTab. 1\u003c/p\u003e\n\u003cp style=\"text-align: center;\"\u003eList of the 100 top-cited articles in intrauterine adhesion research\u003c/p\u003e\n\u003ctable style=\"margin-left: auto; margin-right: auto;\" border=\"1\" width=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003eRank\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003ePublication year\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003eTotal citation\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eTitle\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003ePMCID\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1996\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e253\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eFrequency of factors associated with habitual abortion in 197 couples\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e8752606\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e2\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2000\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e236\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eDiagnostic accuracy at sonohysterography, transvaginal sonography, and hysterosalpingography in patients with uterine cavity diseases\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e10685551\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e3\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1988\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e204\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eIntrauterine adhesions: hysteroscopic diagnosis, classification, treatment, and reproductive outcome\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e3381869\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e4\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2004\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e137\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eEffectiveness of auto-crosslinked hyaluronic acid gel in the prevention of intrauterine adhesions after hysteroscopic surgery: a prospective, randomized, controlled study\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e15105384\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e5\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1978\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e133\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eHysteroscopic management of intrauterine adhesions\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e637078\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e6\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2003\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e129\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eEffectiveness of auto-cross-linked hyaluronic acid gel in the prevention of intrauterine adhesions after hysteroscopic adhesiolysis: a prospective, randomized, controlled study\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e12923149\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e7\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2016\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e119\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eAutologous cell therapy with CD133+bone marrow-derived stem cells for refractory Asherman's syndrome and endometrial atrophy: a pilot cohort study\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e27005892\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e8\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2011\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e117\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eEndometrial regeneration using autologous adult stem cells followed by conception by in vitro fertilization in a patient of severe Asherman's syndrome\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e21772740\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e9\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2003\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e114\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eA comparison of two adjunctive treatments for intrauterine adhesions following lysis\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e12834941\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e10\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2014\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e114\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eBone Marrow-Derived Stem Cell (BMDSC) Transplantation Improves Fertility in a Murine Model of Asherman's Syndrome\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e24819371\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e11\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2008\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e108\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eFactors affecting reproductive outcome of hysteroscopic adhesiolysis for Asherman's syndrome\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e17681324\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e12\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1999\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e102\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eHysteroscopic treatment of severe Asherman's syndrome and subsequent fertility\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e10325268\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e13\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2004\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e99\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003e1000 office-based hysteroscopies prior to in vitro fertilization: feasibility and findings\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e15119651\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e14\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2010\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e97\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eReproductive outcome following hysteroscopic adhesiolysis in patients with infertility due to Asherman's syndrome\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e19455349\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e15\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1998\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e94\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003ePrevalence of Asherman's syndrome after secondary removal of placental remnants or a repeat curettage for incomplete abortion\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e9886512\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e16\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2012\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e93\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eComprehensive management of severe Asherman syndrome and amenorrhea\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e22100167\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e17\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1978\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e91\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eDiagnostic and therapeutic hysteroscopy for traumatic intrauterine adhesions\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e677196\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e18\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1993\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e90\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eIncidence of post-abortion intra-uterine adhesions evaluated by hysteroscopy--a prospective study\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e8473464\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e19\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1997\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e89\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eHysteroscopic treatment of intrauterine adhesions is safe and effective in the restoration of normal menstruation and fertility\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e9418714\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e20\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2008\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e87\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003ePostoperative adhesiolysis therapy for intrauterine adhesions (Asherman's syndrome)\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e18571166\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e21\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2010\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e84\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003ePrevalence of unsuspected uterine cavity abnormalities diagnosed by office hysteroscopy prior to in vitro fertilization\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e20570971\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e22\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1980\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e82\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eHysteroscopy in the evaluation of female infertility\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e7386525\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e23\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2006\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e82\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eAmnion graft following hysteroscopic lysis of intrauterine adhesions\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e17100817\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e24\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2006\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e78\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eFertility after treatment of Asherman's syndrome stage 3 and 4\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e16962521\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e25\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2013\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e77\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eA comparison of intrauterine balloon, intrauterine contraceptive device and hyaluronic acid gel in the prevention of adhesion reformation following hysteroscopic surgery for Asherman syndrome: a cohort study\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e23932377\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e26\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2010\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e75\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eHuman Amnion as a Temporary Biologic Barrier after Hysteroscopic Lysis of Severe Intrauterine Adhesions: Pilot Study\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e20576472\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e27\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1995\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e73\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eReproductive outcome following hysteroscopic management of intrauterine septum and adhesions\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e8567788\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e28\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2004\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e72\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eLive delivery rates in subfertile women with Asherman's syndrome after hysteroscopic adhesiolysis using the resectoscope or the Versapoint system\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e15169591\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e29\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2011\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e72\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eHysteroscopic Management of Residual Trophoblastic Tissue Is Superior to Ultrasound-Guided Curettage\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e22024264\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e30\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2000\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e71\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003ePredictive value of transvaginal sonography performed before routine diagnostic hysteroscopy for evaluation of infertility\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e10685552\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e31\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2006\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e69\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eReduction of postoperative adhesions with an auto-crosslinked hyaluronan gel in gynaecological laparoscopic surgery: a blinded, controlled, randomized, multicentre study\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e16439505\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e32\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1986\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e68\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eSevere obstetric complications after aggressive treatment of Asherman syndrome\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e3703411\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e33\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2013\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e68\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eOptimal waiting period for subsequent fertility treatment after various hysteroscopic surgeries\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e23433831\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e34\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2014\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e66\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eEtiology, treatment, and reproductive prognosis of women with moderate-to-severe intrauterine adhesions\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e24598346\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e35\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2015\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e66\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eHuman CD133(+) bone marrow-derived stem cells promote endometrial proliferation in a murine model of Asherman syndrome\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e26384164\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e36\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2009\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e65\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eUterine synechiae after bipolar hysteroscopic resection of submucosal myomas in patients with infertility\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e18937941\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e37\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2008\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e64\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eEfficiency and pregnancy outcome of serial intrauterine device-guided hysteroscopic adhesiolysis of intrauterine synechiae\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e18774563\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e38\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2010\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e64\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eFertility and pregnancy following pelvic arterial embolisation for postpartum haemorrhage\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e19832826\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e39\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2003\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e63\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eA prospective comparative study between hysterosalpingography and hysteroscopy in the detection of intrauterine pathology in patients with infertility\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e12696625\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e40\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2004\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e62\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eDiagnostic value of hysterosalpingography in the detection of intrauterine abnormalities: A comparison with hysteroscopy\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e15505312\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e41\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2016\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e60\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eAutologous menstrual blood-derived stromal cells transplantation for severe Asherman's syndrome\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e27664218\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e42\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1981\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e58\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eGestational outcome following hysteroscopic lysis of adhesions\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e6269905\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e43\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1988\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e58\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eEndometrial abnormalities: evaluation with transvaginal sonography\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e3275446\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e44\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2008\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e58\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eOffice hysteroscopic early lysis of intrauterine adhesion after transcervical resection of multiple apposing submucous myomas\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e17686478\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e45\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2013\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e57\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eRole of angiogenesis in endometrial repair of patients with severe intrauterine adhesion\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e23826415\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e46\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2014\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e57\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eEffect of stem cell application on Asherman syndrome, an experimental rat model\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e24974357\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e47\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2007\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e56\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eGenital tuberculosis in Indian infertility patients\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e17362955\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e48\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1984\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e54\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eComparison of diagnostic accuracy of laparoscopy, hysteroscopy, and hysterosalpingography in evaluation of female infertility\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e6232154\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e49\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1999\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e54\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eTransvaginal sonohysterographic evaluation of intrauterine adhesions\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e10064410\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e50\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2012\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e52\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eThe effect of collagen-binding vascular endothelial growth factor on the remodeling of scarred rat uterus following full-thickness injury\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e22136717\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e51\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2007\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e51\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eIntrauterine adhesions as a risk factor for failed first-trimester pregnancy termination\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e17900447\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e52\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2006\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e50\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eSuccessful use of vaginal sildenafil citrate in two infertility patients with Asherman's syndrome\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e16724891\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e53\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1976\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e49\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eObstetric complications after treatment of intrauterine synechiae (Asherman's syndrome)\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e934560\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e54\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2011\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e49\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eEfficacy of a Polyethylene Oxide-Sodium Carboxymethylcellulose Gel in Prevention of Intrauterine Adhesions After Hysteroscopic Surgery\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e21777835\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e55\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1979\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e48\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eHysteroscopy in 100 patients\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e437163\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e56\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2015\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e48\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eRandomized, controlled trial comparing the efficacy of intrauterine balloon and intrauterine contraceptive device in the prevention of adhesion reformation after hysteroscopic adhesiolysis\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e25936237\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e57\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1966\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e47\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eThe pathology of postcurettage intrauterine adhesions\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e5928449\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e58\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1998\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e47\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eMyometrial scoring: a new technique for the management of severe Asherman's syndrome\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e9591493\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e59\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2004\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e47\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eHysteroscopy in the evaluation of patients with recurrent pregnancy loss - A cohort study in a primary care population\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e15809790\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e60\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2016\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e47\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eMicroRNA-29b Inhibits Endometrial Fibrosis by Regulating the Sp1-TGF-beta 1/Smad-CTGF Axis in a Rat Model\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e26392347\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e61\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1981\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e45\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eSignificance of intrauterine adhesions detected hysteroscopically in eumenorrheic infertile women and role of antecedent curettage in their formation\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e7468688\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e62\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1985\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e45\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eEtiology of cervical pregnancy. Association with abortion, pelvic pathology, IUDs and Asherman's syndrome\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e4038744\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e63\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2008\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e44\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003ePlacenta Accreta An Association With Fibroids and Asherman Syndrome\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e18946102\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e64\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2014\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e44\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eDoes cold loop hysteroscopic myomectomy reduce intrauterine adhesions? A retrospective study\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e24182410\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e65\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2011\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e43\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eOutpatient hysteroscopy: a routine investigation before assisted reproductive techniques?\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e20638055\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e66\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2013\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e43\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eCreation of a female rabbit model for intrauterine adhesions using mechanical and infectious injury\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e23199550\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e67\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2012\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e42\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eChanges in endometrial receptivity in women with Asherman's syndrome undergoing hysteroscopic adhesiolysis\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e22535194\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e68\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1994\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e41\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003ePost-abortion-hysteroscopy--a method for early diagnosis of congenital and acquired intrauterine causes of abortions\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e7713291\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e69\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2015\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e41\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eResults of centralized Asherman surgery, 2003-2013\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e26428306\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e70\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1992\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e40\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eHysteroscopic findings after missed abortion\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1521644\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e71\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1993\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e40\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eInduced regeneration of endometrium following curettage for abortion: a comparative study\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e8408501\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e72\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2007\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e40\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eFluoroscopically guided synechiolysis for patients with Asherman's syndrome: menstrual and fertility outcomes\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e17109860\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e73\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1997\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e39\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eSuccessful treatment of severe uterine synechiae with transcervical resectoscopy combined with laminaria tent\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e9194644\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e74\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2005\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e39\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003ePathologic findings in hysteroscopy before in vitro fertilization-embryo transfer (IVF-ET)\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e16316847\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e75\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2014\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e39\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eDiagnostic accuracy of three-dimensional sonohysterography compared with office hysteroscopy and its interrater/intrarater agreement in uterine cavity assessment after hysteroscopic metroplasty\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e24581576\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e76\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1989\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e38\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eValue of intrauterine device insertion and estrogen administration after hysteroscopic metroplasty\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e2549238\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e77\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2008\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e38\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eThin unresponsive endometrium-a possible complication of surgical curettage compromising ART outcome\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e18797990\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e78\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1983\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e37\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eDiagnosis and treatment of intrauterine adhesions by microhysteroscopy\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e6825866\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e79\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2017\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e37\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003ePrevalence of intrauterine adhesions after the application of hyaluronic acid gel after dilatation and curettage in women with at least one previous curettage: short-term outcomes of a multicenter, prospective randomized controlled trial\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e28390688\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e80\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2018\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e37\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eAllogeneic cell therapy using umbilical cord MSCs on collagen scaffolds for patients with recurrent uterine adhesion: a phase I clinical trial\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e29996892\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e81\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2010\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e36\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eResults of 2500 office-based diagnostic hysteroscopies before IVF\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e20207586\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e82\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2017\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e36\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eReproductive Outcomes in Patients With Intrauterine Adhesions Following Hysteroscopic Adhesiolysis: Experience From the Largest Women's Hospital in China\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e27856386\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e83\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2017\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e36\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eEffects of Aspirin and Intrauterine Balloon on Endometrial Repair and Reproductive Prognosis in Patients with Severe Intrauterine Adhesion: A Prospective Cohort Study\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e28251159\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e84\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1976\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e35\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eIntrauterine adhesions secondary to elective abortion. Hysteroscopic diagnosis and management\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e\u0026nbsp;\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e85\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1992\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e35\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eDiagnostic hysteroscopy: its value in an in-vitro fertilization/embryo transfer unit\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1291572\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e86\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1996\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e35\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eHysteroscopic management of uterine synechiae: a series of 102 observations\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e8730623\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e87\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1999\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e35\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eFluoroscopically guided hysteroscopic division of adhesions in severe Asherman syndrome\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e10362178\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e88\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2000\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e35\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eOperative hysteroscopy for infertility using normal saline solution and a coaxial bipolar electrode: a pilot study\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e10920101\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e89\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2007\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e35\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003ePrevalence of uterine synechia after abortion evacuation curettage\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e18094891\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e90\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2008\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e35\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eGenital tuberculosis: an important cause of Asherman's syndrome in India\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e17653564\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e91\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2016\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e35\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eEndometrial stem cells repair injured endometrium and induce angiogenesis via AKT and ERK pathways\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e27486270\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e92\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2015\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e34\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003ePreventive effect of oral mucosal epithelial cell sheets on intrauterine adhesions\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e25475585\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e93\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2007\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e33\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eHysteroscopy after uterine fibroid embolization in women of fertile age\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e17578361\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e94\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2016\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e33\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eThe influence of the location and extent of intrauterine adhesions on recurrence after hysteroscopic adhesiolysis\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e25753391\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e95\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e2017\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e33\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eHuman amniotic mesenchymal stromal cell transplantation improves endometrial regeneration in rodent models of intrauterine adhesions\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e28285950\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e96\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1982\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e32\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eAsherman's syndrome. A comparison of therapeutic methods\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e7120210\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e97\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1995\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e31\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003ePreoperative sonographic measurement of endometrial pattern predicts outcome of surgical repair in patients with severe Asherman's syndrome\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e7843453\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e98\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1996\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e31\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eIntrauterine adhesions: detection with transvaginal US\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e8638001\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e99\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1999\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e31\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eTotal corporal synechiae due to tuberculosis carry a very poor prognosis following hysteroscopic synechialysis\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e10438408\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"49\"\u003e\n\u003cp\u003e100\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"91\"\u003e\n\u003cp\u003e1997\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"64\"\u003e\n\u003cp\u003e30\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"340\"\u003e\n\u003cp\u003eSimplified therapy for Asherman's syndrome\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e9418695\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003eThese articles were distributed in 22 countries (Fig. 4), led by China (n=19) followed by the USA (n=18), France (n=8), Israel (n=8), and Italy (n=8). The allocation is presented on the world map (Fig. 5). In terms of regional distribution, most of the articles published from two countries: America and Asia. The rest were scattered in Europe, Africa and Oceania. Developed countries accounted for 67% of all countries mentioned above. Articles were all published in 33 journals, among which 27 articles were published in \"Fertility and sterility\", followed by \"Human Reproduction\" (n=16), American journal of obstetrics and gynecology\" (n=6), \"Journal of Minimally Invasive Gynecology\" (n=5). (Table 2).\u003c/p\u003e\n\u003cp style=\"text-align: center;\"\u003eTab. 2\u003c/p\u003e\n\u003cp style=\"text-align: center;\"\u003eJournals of the 100 top-cited studies published.\u003c/p\u003e\n\u003ctable style=\"margin-left: auto; margin-right: auto;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003ePublication\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003eNumber account\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003eTotal citation\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003eAverage citation\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003eIF (2020)\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eFertility and sterility\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e27\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e1895\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e70\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e6.3\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eHuman Reproduction\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e16\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e1171\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e73\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e5.7\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eAmerican journal of obstetrics and gynecology\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e6\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e602\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e100\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e6.5\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eJournal of Minimally Invasive Gynecology\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e5\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e310\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e62\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e3.1\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eObstetrics and Gynecology\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e4\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e187\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e47\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e5.5\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eArchives of Gynecology and Obstetrics\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e3\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e174\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e58\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e2.3\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eEuropean journal of obstetrics, gynecology, and reproductive biology\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e3\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e153\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e51\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e1.9\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eInternational Journal of Gynecology \u0026amp; Obstetrics\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e3\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e236\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e79\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e2.2\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eJournal of Obstetrics and Gynaecology Research\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e3\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e178\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e59\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e1.4\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eThe Journal of reproductive medicine\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e3\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e115\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e38\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e0.2\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eBjog-an International Journal of Obstetrics and Gynaecology\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e2\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e97\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e49\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e4.7\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eJournal of Assisted Reproduction and Genetics\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e2\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e95\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e48\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e2.8\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eReproductive Biomedicine Online\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e2\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e108\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e54\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e3.2\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eAJR. American journal of roentgenology\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e58\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e58\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e3.0\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eAmerican Journal of Roentgenology\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e62\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e62\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e3.0\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eBiomaterials\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e52\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e52\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e10.3\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eBiomed Research International\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e36\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e36\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e2.3\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eContraception\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e51\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e51\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e2.8\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eCytotherapy\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e33\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e33\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e4.2\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eGynecological Endocrinology\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e39\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e39\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e1.6\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eInternational Journal of Clinical and Experimental Pathology\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e57\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e57\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e0.3\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eJournal of human reproductive sciences\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e54\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e54\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e0.8\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eJournal of Clinical Ultrasound\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e117\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e117\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e1.0\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eJournal of Surgical Research\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e43\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e43\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e1.8\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eJournal of Ultrasound in Medicine\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e44\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e44\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e1.8\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eJournal of Womens Health\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e50\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e50\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e1.9\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eJSLS: Journal of the Society of Laparoendoscopic Surgeons\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e99\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e99\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e1.5\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003ePlos One\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e114\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e114\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e2.7\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eRadiology\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e31\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e31\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e7.9\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eReproduction\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e35\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e35\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e3.2\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eReproductive Sciences\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e47\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e47\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e2.6\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eSao Paulo Medical Journal\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e35\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e35\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e1.0\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eStem Cell Research \u0026amp; Therapy\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e37\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e37\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e5.1\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"284\"\u003e\n\u003cp\u003eSurgical Endoscopy and Other Interventional Techniques\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"65\"\u003e\n\u003cp\u003e47\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"67\"\u003e\n\u003cp\u003e47\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"62\"\u003e\n\u003cp\u003e3.1\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003eAmong the 100 highly cited articles, 10 researchers have more than two articles which is listed in Table 3. These authors\u0026rsquo; articles are all clinical studies related to IUA. Among them, CM March and Jehn-Hsiahn Yang had 3 fist authorships mainly in the field of IUA. CM March\u0026rsquo;s focus was on hysteroscopic adhesiolysis, and Jehn-Hsiahn Yang\u0026rsquo;s research direction was endometrium regeneration. Although R F Valle from the United States had only two articles, the number of citations is relatively high, with an overall number of citations of 286. Auxiliary diagnosis of IUA is his main focus.\u003c/p\u003e\n\u003cp style=\"text-align: center;\"\u003eTab. 3\u003c/p\u003e\n\u003cp style=\"text-align: center;\"\u003eList of first authors with frequent articles within the top-cited list.\u003c/p\u003e\n\u003ctable style=\"margin-left: auto; margin-right: auto;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"95\"\u003e\n\u003cp\u003eFirst Author\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003eNumber of Study\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003eCitations Account\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"327\"\u003e\n\u003cp\u003eAuthor\u0026rsquo;s Affiliation\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"95\"\u003e\n\u003cp\u003eC M March\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e3\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e226\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"327\"\u003e\n\u003cp\u003eDepartment of Obstetrics and Gynecology, University of Southern California School of Medicine Los Angeles, California, USA.\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"95\"\u003e\n\u003cp\u003eJehn-Hsiahn Yang\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e3\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e159\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"327\"\u003e\n\u003cp\u003eDepartment of Obstetrics and Gynecology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"95\"\u003e\n\u003cp\u003eR F Valle\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e2\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e286\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"327\"\u003e\n\u003cp\u003eDepartment of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinios, USA\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"95\"\u003e\n\u003cp\u003eMohamed I Amer\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e2\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e157\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"327\"\u003e\n\u003cp\u003eDepartment of Obstetrics and Gynecology, Ain Shams University, Cairo, Egypt.\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"95\"\u003e\n\u003cp\u003eRecai Pabuccu\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e2\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e153\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"327\"\u003e\n\u003cp\u003eDepartment of Obstetrics and Gynecology, G\u0026uuml;lhane School of Medicine, Ankara, Turkey.\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"95\"\u003e\n\u003cp\u003eXiaona Lin\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e2\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e125\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"327\"\u003e\n\u003cp\u003eCenter of Reproductive Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, PR China.\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"95\"\u003e\n\u003cp\u003eH Fernandez\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e2\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e113\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"327\"\u003e\n\u003cp\u003eDepartment of Obstetrics and Gynaecology, Antoine B\u0026eacute;cl\u0026egrave;re Hospital, Clamart Cedex, France.\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"95\"\u003e\n\u003cp\u003eYuqing Chen\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e2\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e93\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"327\"\u003e\n\u003cp\u003eDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"95\"\u003e\n\u003cp\u003eP J Taylor\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e2\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e93\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"327\"\u003e\n\u003cp\u003eDepartment of Obstetrics and Gynecology, University of Calgary and Foothills Hospital, Calgary, Alberta, Canada\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"95\"\u003e\n\u003cp\u003eA Golan\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e2\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"66\"\u003e\n\u003cp\u003e75\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"327\"\u003e\n\u003cp\u003eDepartment of Obstetrics and Gynecology, Assaf Harofeh Medical Center, Zerifin, Israel.\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u003cbr /\u003eThe 100 most cited articles mainly focus on the following themes: auxiliary treatment of IUA (n = 28), prognosis of IUA (n=19), incentive factors of IUA (n=16), hysteroscopic adhesiolysis (n=14), evaluation methods for IUA (n=12), complications of IUA (n = 6), relevant mechanism of IUA (n = 4), new devices for IUA (n=1). The most mentioned theme was the adjuvant treatment of IUA, followed by the reproductive prognosis of patients after hysteroscopic adhesiolysis (Fig. 6). One-way ANOVA revealed no significant difference in citations per article among the various themes (Fig. 7). Nevertheless, the impact factor of article from different themes was statistically different (P=0.012) (Fig. 8).\u003c/p\u003e\n\u003cp\u003eIn terms of the level of article evidence, the level II (n=39) category has a mean number of 69 \u0026plusmn; 48 citations per article, making up the largest number. The level I (n=23) category has a mean number of 63\u0026plusmn;30 citations per article, the level IV (n=14) with 48\u0026plusmn;22 citations. Difference in citations per article between different levels of evidence is not significant analyzed by one-way ANOVA (Fig. 9).\u003c/p\u003e\n\u003cp\u003eNetwork analysis of the key words or subject terms has been done in two periods of article published time: in the 2000s (34 articles) and in the 2010s (30 articles). The result indicated that \"hysteroscopy\", \"hysteroscopic adhesiolysis\", \"infertility\", and \"reproductive outcome\" possessed a high degree of centrality in the 2000s and 2010s, while \"placenta accrete\" were greatly centralized in the 2000s and \"stem cell\" and \"fibrosis\" was highly concentrated in the 2010s (Fig. 10-11).\u003c/p\u003e"},{"header":"Discussion","content":" \u003cp\u003eThis is the first bibliometric analysis of papers in the field of IUA. Mass of interesting findings can be drawn from this analysis of the top 100 most cited papers published on IUA in the past 70 years. Not only the papers which had made important contributions to the progress in this field were reflected, but also current development trend was revealed. Generally speaking, with the time goes by, the number of citations of papers would be piled up. However, it is contrary to expectation that the number of articles was gradually increasing as time progresses when we assessed the certain 100 most cited articles according to the division of each decade. Articles in 2010s possessed the highest proportion, reaching 35%. As time increases, not only the proportion of articles presented an growing trend, but also the citation density, that is, the number of citations divided by the number of years of publication, figured an increasing trend. On the one hand, this reflects the \"obliteration by incorporation\" (\u003cspan citationid=\"CR39\" class=\"CitationRef\"\u003e39\u003c/span\u003e), that is, the citations of the original work decreased with the passage of time for familiarity during the long-term and widespread use, and new findings replaced them. On the other hand, this also presented the phenomenon that the diagnosis, treatment and advanced researches related to IUA have been paid more and more attention by the international community. In addition, 91% of these articles were clinical studies, and only 9% were basic experimental studies. Those basic studies mentioned above were all published in the 2010s. We may say that clinical research has always been the focus of researchers in the field of IUA. However, the disease mechanism is also crucial to the treatment of the disease. Current researches on the mechanism had an increasing trend, and it has the potential to provide clinical directions in the future.\u003c/p\u003e \u003cp\u003eDifferent from the trend of other bibliometric analysis reports, articles originating from the United States and developed countries did not have an absolute advantage. China and the United States were both important sources of articles, with 19 and 18 articles respectively. 33% of the 100 most cited papers were from developing countries, 67% were from developed countries. There are several reasons for this condition: (\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e) The clinical manifestations of IUA were first reported in the United States in the 19th century, and later defined and named by American doctors. Therefore, they were able to study it earlier and more systematically (\u003cspan citationid=\"CR40\" class=\"CitationRef\"\u003e40\u003c/span\u003e);The United States and other developed countries had sufficient funds to support scientific research. The sharing of these research results will help the progress of researches on IUA (\u003cspan citationid=\"CR41\" class=\"CitationRef\"\u003e41\u003c/span\u003e, \u003cspan citationid=\"CR42\" class=\"CitationRef\"\u003e42\u003c/span\u003e); (\u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e) As we all know, the occurrence of IUA is closely related to abortion and curettage. Honestly, abortion is considered illegal in many developing countries due to religious beliefs. In developed countries, the rate of abortion dropped by 19 percentage points from 1990 to 2014, while it only fell by 2 percentage points in developing countries (\u003cspan citationid=\"CR43\" class=\"CitationRef\"\u003e43\u003c/span\u003e). Moreover, least-safe abortions accounted for the largest proportion in developing countries (\u003cspan citationid=\"CR44\" class=\"CitationRef\"\u003e44\u003c/span\u003e); (\u003cspan citationid=\"CR3\" class=\"CitationRef\"\u003e3\u003c/span\u003e) China and other developing countries had great population. Propaganda and popularization of contraceptive measures were inadequate. It was inevitable to choose surgical abortion after unintended pregnancy. Repeated or informal intrauterine operations may finally lead to irreversible hurt to endometrium (\u003cspan citationid=\"CR45\" class=\"CitationRef\"\u003e45\u003c/span\u003e, \u003cspan citationid=\"CR46\" class=\"CitationRef\"\u003e46\u003c/span\u003e); (\u003cspan citationid=\"CR4\" class=\"CitationRef\"\u003e4\u003c/span\u003e) After China opened up the two-child policy, more and more IUA were discovered, and recurrent IUA need to be treated (\u003cspan citationid=\"CR47\" class=\"CitationRef\"\u003e47\u003c/span\u003e, \u003cspan citationid=\"CR48\" class=\"CitationRef\"\u003e48\u003c/span\u003e). IUA is a universal disease, but unfortunately, no multinational cooperation work was found in these 100 most cited papers.\u003c/p\u003e \u003cp\u003eActually, the impact factors of journals were not high. This was because related papers were rarely published in comprehensive journals, while the impact factors of obstetrics and gynecology professional journals are relatively low. This result highlighted a growing tendency that researchers may prefer to publish articles in influential professional journals. However, there was no denying that the value of IUA researches have not been highly appreciated.\u003c/p\u003e \u003cp\u003eNearly 50% of the certain 100 papers were issued in two journals, \u0026ldquo;Fertility and sterility\u0026rdquo; and \u0026ldquo;Human Reproduction\u0026rdquo;, followed closely by two heavyweight journals in the field of obstetrics and gynecology, \u0026ldquo;American journal of obstetrics and gynecology\u0026rdquo; and \u0026ldquo;Obstetrics and Gynecology\u0026rdquo;. This demonstrated that IUA were particularly concerned in the field of reproductive medicine. Among the 100 most cited articles, the themes of papers published in recent years appeared to be more diverse, including the Phase I clinical study of autologous stem cell transplantation for the treatment of IUA published in Stem Cell Research \u0026amp; Therapy (\u003cspan citationid=\"CR49\" class=\"CitationRef\"\u003e49\u003c/span\u003e), and collagen scaffold for endometrial regeneration published in Biomaterials (\u003cspan citationid=\"CR50\" class=\"CitationRef\"\u003e50\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eWhen it comes to the first author of the 100 most cited papers, we found that 2 researchers contributed 3 articles. One of them was Charles M. March from the United States. His articles were all published before 1990, and emphasized that hysteroscopy is the gold standard for diagnosis and classification of IUA, and hysteroscopic adhesiolysis is the first choice for the treatment of IUA (\u003cspan additionalcitationids=\"CR52\" citationid=\"CR51\" class=\"CitationRef\"\u003e51\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR53\" class=\"CitationRef\"\u003e53\u003c/span\u003e). The other one was Jehn-Hsiahn Yang from Taiwan, China, a younger generation of researchers. The similarity with Charles M. March was that they both focus on hysteroscopy. His three articles have proposed that IUA was common complications after transcervical resection of multiple apposing submucous myomas (\u003cspan citationid=\"CR54\" class=\"CitationRef\"\u003e54\u003c/span\u003e), the formation of new adhesions after hysteroscopic adhesiolysis was the reason that affects endometrial repair (\u003cspan citationid=\"CR55\" class=\"CitationRef\"\u003e55\u003c/span\u003e), the location and area of adhesions were important factors that affect the recurrence of IUA (\u003cspan citationid=\"CR15\" class=\"CitationRef\"\u003e15\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eThe level of evidence was between I and V. The overall distribution was average, and level II was relatively high, which is distinct with other bibliometric-related studies. This may attribute to the design of clinical trials. Treatment of IUA was closely related to patients\u0026rsquo; reproductive prognosis, and for women, age was also a significant factor. Therefore, considering the effect of placebo control on patients, experimental studies are mostly unilateral. In the future, with the increase in the demand for childbirth and the introduction of two or even three-child opening policies in some countries, it is expected that hysteroscopic adhesiolysis, postoperative adjuvant treatment and related research articles will increase more rapidly.\u003c/p\u003e \u003cp\u003eWe also studied the theme distribution of articles. The adjuvant treatment of IUA ranked first, followed by the prognosis of reproductive outcome after hysteroscopic adhesiolysis, the incentive factors of IUA, hysteroscopic adhesiolysis and the evaluation method of IUA. Hysteroscopic adhesiolysis is the primary treatment method. However, how to improve the therapeutic effect through drugs and biological agents after the surgery has been a problem that researchers want to overcome in recent years (\u003cspan citationid=\"CR56\" class=\"CitationRef\"\u003e56\u003c/span\u003e). Network analysis of the author\u0026rsquo;s key words or subject terms has been done in two periods of article published time: in the 2000s (34 articles) and in the 2010s (30 articles). The result indicated that \u0026ldquo;\"hysteroscopy, hysteroscopic adhesiolysis, infertility and reproductive outcome\" was highly centralized in both 2000s and 2010s and placental implantation was highly concentrated in the 2000s. This was consistent with the research trend in recent years. Researchers have gradually realized that even if patients with IUA succeed in conception, there would be many risks of pregnancy complications. The most cited article in this study was also an article about IUA complications, in which the author proposed that patients with IUA were associated with many risks during pregnancy. An analysis of the citation density of papers published in the 2010s, we found each theme was evenly distributed. In the analysis of the impact factor under each theme, it could be seen that articles related to devices and materials were relatively high, while researches on mechanism were relatively low. Stem cell and fibrosis were highly concentrated in the 2010s. In recent years, researchers have paid more and more attention to the effectiveness of adjuvant therapy after hysteroscopic adhesiolysis in suppressing reformation of adhesion and promoting endometrial regeneration (\u003cspan citationid=\"CR57\" class=\"CitationRef\"\u003e57\u003c/span\u003e). Previous researches focused on placement of uterine stents, foley catheters, hyaluronic acid or hormone replacement therapy (\u003cspan citationid=\"CR58\" class=\"CitationRef\"\u003e58\u003c/span\u003e). Nevertheless, more importance was attached to biotherapy, especially in the field of stem cell therapy. Bone marrow mesenchymal stem cells (BMSC) (\u003cspan citationid=\"CR59\" class=\"CitationRef\"\u003e59\u003c/span\u003e), umbilical cord mesenchymal stem cells (UCMSC) (\u003cspan citationid=\"CR60\" class=\"CitationRef\"\u003e60\u003c/span\u003e), and menstrual blood mesenchymal stem cells (MbMSC) (\u003cspan citationid=\"CR61\" class=\"CitationRef\"\u003e61\u003c/span\u003e, \u003cspan citationid=\"CR62\" class=\"CitationRef\"\u003e62\u003c/span\u003e) have been used clinically in patients with IUA, resulting in an improvement in reproductive outcome. Researchers reported that the stem cells can promote endometrial cells proliferation, especially inhibit the process of fibrosis (\u003cspan citationid=\"CR63\" class=\"CitationRef\"\u003e63\u003c/span\u003e). In 2020, a review brought together the controversies of different researchers on the treatment of IUA (\u003cspan citationid=\"CR64\" class=\"CitationRef\"\u003e64\u003c/span\u003e). One believed that the adjuvant treatment after the surgery should be paid attention to, and another believed that IUA should be treated with multiple operations. However, it cannot be ignored that, hysteroscopic adhesiolysis has always been the center of research over the years, and the discussion of surgical methods and surgical techniques was still a vacancy (\u003cspan citationid=\"CR65\" class=\"CitationRef\"\u003e65\u003c/span\u003e) It is undeniable that the combined effective adjuvant treatment after surgery is the trend of IUA treatment.\u003c/p\u003e \u003cp\u003eThis analysis does generate some valuable information, but it still has some restrictions. First of all, the citation analysis was mainly based on Web of Science. The number of citations may be misleading. Meanwhile, we may miss some important papers that were not included in the SCI database. Secondly, we may overlook the newly published articles that were meaningful in this area but have yet to reach high citation levels owing to the criterion that papers were sorted by the number of citations. All in all, it was by no means exhaustive, but the list of most cited articles still includes many influential papers in the field of IUA.\u003c/p\u003e "},{"header":"Conclusion","content":" \u003cp\u003eThis article highlights the top 100 most cited articles in the IUA over the last 70 years, including their publication time and regional centers, first author, level of evidence, as well as their research theme. We revealed the spotlights and properties of studies about IUA since 1950 to 2020. Furthermore, this article sheds light on the notion that postoperative adjuvant therapy played a key role in the field of IUA, and more and more basic and clinical studies are exploring suitable and effective adjuvant treatments for IUA. Meanwhile, the method and techniques of surgical therapy is also controversial. However, the current prognosis of IUA was extremely poor. The tough problem still remains to be solved. Researchers extremely focused on the clinical trial rather than the basic laboratory research. Thus, the foremost difficult is to conquer the situation that little is known about underlying mechanisms of adhesion formation in the uterine and influencing factors.\u003c/p\u003e "},{"header":"Abbreviations","content":"\u003cp\u003e\u003cstrong\u003eIUA\u003c/strong\u003e: intrauterine adhesion\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eIUD\u003c/strong\u003e: intrauterine device\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eACP\u003c/strong\u003e: auto-crosslinked hyaluronic acid\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eBMSC\u003c/strong\u003e: bone marrow mesenchymal stem cells\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eUCMSC\u003c/strong\u003e: umbilical cord mesenchymal stem cells\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eMbMSC\u003c/strong\u003e: menstrual blood mesenchymal stem cells\u003c/p\u003e"},{"header":"Declarations","content":"\u003ch2\u003eEthics approval and consent to participate\u003c/h2\u003e\n\u003cp\u003eNot applicable\u003c/p\u003e\n\u003ch2\u003eConsent for publication\u003c/h2\u003e\n\u003cp\u003eNot applicable\u003c/p\u003e\n\u003ch2\u003eAvailability of data and materials\u003c/h2\u003e\n\u003cp\u003eNot applicable\u003c/p\u003e\n\u003ch2\u003eCompeting interests\u003c/h2\u003e\n\u003cp\u003eThe authors declare that they have no competing interests.\u003c/p\u003e\n\u003ch2\u003eFunding\u003c/h2\u003e\n\u003cp\u003eThis study was supported by the National Key Research and Development Program of China (grant no. 2018YFC1004800).\u003c/p\u003e\n\u003ch2\u003eAuthors' contributions\u003c/h2\u003e\n\u003cp\u003eDX contributed to the design of the study and revise the manuscript. PG and WL contributed to the process of searching, selecting and drafting the manuscript.\u003c/p\u003e\n\u003ch2\u003eAcknowledgements\u003c/h2\u003e\n\u003cp\u003eNot applicable\u003c/p\u003e\n\u003ch2\u003eFootnotes\u003c/h2\u003e\n\u003cp\u003eNot applicable\u003c/p\u003e\n\u003cp\u003e\u0026nbsp;\u003c/p\u003e"},{"header":"References","content":"\u003col\u003e\n\u003cli\u003eAsherman JG. Traumatic intra-uterine adhesions. J Obstet Gynaecol Br Emp. 1950;57(6):892-6.\u003c/li\u003e\n\u003cli\u003eWang Y, Yao Z, Zhao H, Yue C, Yu Q, Zhang Y, et al. Reproductive Outcomes of In Vitro Fertilization-Intracytoplasmic Sperm Injection after Transcervical Resection of Adhesions: A Retrospective Cohort Study. J Minim Invasive Gynecol. 2020.\u003c/li\u003e\n\u003cli\u003eHooker AB, de Leeuw RA, Twisk JWR, Br\u0026ouml;lmann HAM, Huirne JAF. 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Ann Transl Med. 2020;8(11):663.\u003c/li\u003e\n\u003c/ol\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Intrauterine adhesion, hysteroscopy, hysteroscopic adhesiolysis, bibliometric analysis","lastPublishedDoi":"10.21203/rs.3.rs-345211/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-345211/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground\u003c/strong\u003e: Bibliometric analysis is a statistical method which attempts to assess articles by their citations, analyzing their frequency and pattern of citing phenomenon. Through the analysis, some guidance can be extracted for future research directions. Over the past few years, there have been articles published in mounting numbers focused on intrauterine adhesions. Nevertheless, little is known about the properties and qualities of these researches. No existed analysis commits to reflecting the progress of researches in intrauterine adhesion.\u003c/p\u003e\u003cp\u003e\u003cstrong\u003eMethods\u003c/strong\u003e: Web of Science Core Collection, BIOSIS Citation Index and MEDLINE were searched for the identifying articles released from 1950 to October 2020. Articles concerning about Intrauterine adhesion were determined. Subsequently, the 100 most cited articles were chosen for analysis of citation count, citation density (citations/article age), authorship, theme, geographic distribution, time-related flux, level of evidence, and network analysis.\u003c/p\u003e\u003cp\u003e\u003cstrong\u003eResults\u003c/strong\u003e: An overwhelming majority of the certain 100 articles were put out in the 2010s (35%). Citations per article ranged from 30 to 253. China possesses the most papers among the top 100 papers, followed by the USA, France, Israel and Italy. The study theme that most highlighted were operative hysteroscopy and adjunctive treatments for improving reproductive outcome. Level II is the most common level of evidence, and there is no statistical difference in the number of citations between the levels. The network analysis connoted that hysteroscopy, hysteroscopic adhesiolysis, infertility, and reproductive outcome had a great degree of centrality in the 2000s and 2010s, while placental implantation had a great degree of centrality in the 2000s and stem cell and fibrosis had a great degree of centrality in the 2010s. \u003c/p\u003e\u003cp\u003e\u003cstrong\u003eConclusions\u003c/strong\u003e: We conducted a bibliometric analysis of the top 100 most cited articles in the literature on intrauterine adhesions. It is worth noting that hysteroscopy and hysteroscopic adhesiolysis were long-term concern in the field of intrauterine adhesion researches. As the elapse of time, postoperative adjuvant treatment has gradually become the hot spot of researches. However, there are only 9 experimental articles among these 100 articles, showing the lack of breakthrough progress in the field of intrauterine adhesions at the mechanism level.\u003c/p\u003e","manuscriptTitle":"The Top 100 Most Cited Articles on Intrauterine Adhesion: A Bibliometric Analysis","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2021-04-06 16:03:54","doi":"10.21203/rs.3.rs-345211/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"c713726e-4c27-4b85-be1c-2fba9429cdd8","owner":[],"postedDate":"April 6th, 2021","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"published-in-journal","subjectAreas":[{"id":3443528,"name":"Sexual \u0026 Reproductive Medicine"}],"tags":[],"updatedAt":"2021-11-15T16:42:44+00:00","versionOfRecord":{"articleIdentity":"rs-345211","link":"https://doi.org/10.1007/s43032-021-00794-x","journal":{"identity":"reproductive-sciences","isVorOnly":false,"title":"Reproductive Sciences"},"publishedOn":"2021-11-15 16:42:44","publishedOnDateReadable":"November 15th, 2021"},"versionCreatedAt":"2021-04-06 16:03:54","video":"","vorDoi":"10.1007/s43032-021-00794-x","vorDoiUrl":"https://doi.org/10.1007/s43032-021-00794-x","workflowStages":[]},"version":"v1","identity":"rs-345211","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-345211","identity":"rs-345211","version":["v1"]},"buildId":"re_ckhLnmML6MCF96OHNJ","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}