The Role of the Oxygen Hole in Hydrolases
preprint
OA: closed
Abstract
The oxygen hole is ubiquitous in hydrolase and lowers the activation energy of the transition state. Its geometry invites the formation of a low energy tetrahedron facilitating electronic movements. In effect it functions as a switch.
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- europepmc
- last seen: 2026-05-20T01:45:00.602351+00:00