Laparoscopic surgery improves pregnancy outcomes in women with suspected endometriosis with or without pathological confirmation

P B Miller, Miller PB, Savaris RF, R F Savaris, D A Forstein, Forstein DA, Likes CE, C E Likes, Nichols C, C. Nichols, L J Cooper, Cooper LJ, B A Lessey, Lessey BA
Clinical and experimental obstetrics & gynecology · 2016 · doi:10.12891/ceog2030.2016 · PMID:27048014
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-07-21 ⓘ

Laparoscopic surgery for suspected endometriosis in women with unexplained infertility yielded similar pregnancy outcomes regardless of pathological confirmation of the disease.

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This study investigated whether histological confirmation of endometriosis influences fertility outcomes in women undergoing laparoscopic surgery for unexplained infertility. Researchers analyzed data from 103 patients who underwent excision or ablation of suspected lesions, comparing pregnancy rates and time to conception between those with pathological confirmation and those without. The results indicated no significant difference in clinical pregnancy rates or time to conceive between the two groups, suggesting that visual suspicion alone is sufficient for treatment decisions. This paper is centrally about endometriosis — specifically evaluating the impact of pathological confirmation on pregnancy outcomes following laparoscopic intervention for suspected disease.

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Abstract

PURPOSE OF THE INVESTIGATION: To verify whether histologic confirmation of endometriosis impacts fertility outcomes. MATERIALS AND METHODS: Women with unexplained infertility (UI) underwent laparoscopic excision or ablation with CO2 laser or electrocautery of all suspected endometriotic lesions, followed by clinical treatment between January 2007 and December 2013; pregnancy (> 12 weeks) within 12 months of monitored cycles was the main outcome measured. RESULTS: Women with histological confirmation (n = 74) did not differ from those not confirmed (n = 29) with age, body mass index, gravidity, parity, ovulation induction protocol, and past duration of infertility. Pregnancy outcome was similar in both groups (39/74 vs. 15/29-p = 0.9--Chi-square) and there was no statistical difference in time to conceive/deliver (p = 0.7) between groups. CONCLUSIONS: There is no difference in fertility outcomes in women with UI, whether or not suspected endometriosis is confirmed pathologically.
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Abstract

Purpose of the investigation: To verify whether histologic confirmation of endometriosis impacts fertility outcomes. Materials and Methods: Women with unexplained infertility (UI) underwent laparoscopic excision or ablation with CO2 laser or electrocautery of all suspected endometriotic lesions, followed by clinical treatment between January 2007 and December 2013; pregnancy (> 12 weeks) within 12 months of monitored cycles was the main outcome measured. Results: Women with histological confirmation (n=74) did not differ from those not confirmed (n=29) with age, body mass index, gravidity, parity, ovulation induction protocol, and past duration of infertility. Pregnancy outcome was similar in both groups (39/74 vs. 15/29 - p = 0.9 – Chi-square) and there was no statistical difference in time to conceive/deliver (p = 0.7) between groups. Conclusions: There is no difference in fertility outcomes in women with UI, whether or not suspected endometriosis is confirmed pathologically.

Keywords

- Laparoscopy - Endometriosis - Pregnancy outcome

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Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Gynecologic Surgical Procedures Infertility, Female Laparoscopy Pregnancy Complications Adult Endometriosis Endometriosis Endometriosis Female Fertility Gynecologic Surgical Procedures Humans Infertility, Female Infertility, Female Laparoscopy Pregnancy Pregnancy Complications Pregnancy Outcome Young Adult

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europepmc
last seen: 2026-09-30T06:18:36.089610+00:00
pubmed
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