Histidine-(N-benzyl glycinamide) inhibitors of protein farnesyl transferase

DOBRUSIN ELLEN M, DOHERTY ANNETTE M, KALTENBRONN JAMES S, LEONARD DANIELE M, MCNAMARA DENNIS J, SEBOLT-LEOPOLD Judith, SHULER KEVON R
2001
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Histidine-(N-benzyl glycinamide) inhibitors of protein farnesyl transferase were developed and described for potential treatment of endometriosis among other conditions.

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Abstract

Inhibitors of protein farnesyl transferase enzymes are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in treating cancer, restenosis, psoriasis, endometriosis, atherosclerosis, or viral infections.

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europepmc
last seen: 2026-08-13T06:15:24.848197+00:00