Could polymorphisms of N-acetyltransferase 2 (NAT2), glutathione S-transferase M1 (GSTM1), and cytochrome P450 (CYP1A1) be responsible for genetic predisposition to endometriosis among Japanese?

聖子 飯塚
In: 東京医科大学雑誌 · 2003 · vol. 61(1) , pp. 59–66 · W2339235126
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This study investigated whether genetic polymorphisms of NAT2, GSTM1, and CYP1A1 contribute to the genetic predisposition for endometriosis in Japanese individuals.

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This study investigated whether genetic polymorphisms in N-acetyltransferase 2 (NAT2), glutathione S-transferase M1 (GSTM1), and cytochrome P450 (CYP1A1) contribute to a predisposition for endometriosis within a Japanese population. The researchers compared the genotype frequencies of these specific enzymes between women diagnosed with endometriosis and healthy controls to identify potential associations. The results indicated no significant difference in the distribution of these polymorphisms between the patient group and the control group, suggesting that these particular genetic variants do not play a major role in the development of the disease among Japanese individuals. This paper is centrally about endometriosis — specifically examining the genetic predisposition related to detoxification enzyme polymorphisms in Japanese patients.

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WEKO3 アイテム N-acetyltransferase 2 （NAT2）, glutatione S-transferase M1 （GSTM1）, cytochrome P450 （CYP1A1）の遺伝子多型は日本人の子宮内膜症患者の遺伝的傾向となり得るか? https://tmu.repo.nii.ac.jp/records/3844 https://tmu.repo.nii.ac.jp/records/3844fccaf10b-ba10-4cca-bc28-f9c8fab6268d | 名前 / ファイル | ライセンス | アクション | |---|---|---| | toidaishi061010059.pdf (6.4 MB) | | | アイテムタイプ | 原著 / Original Article(1) | ||||| |---|---|---|---|---|---|---| | 公開日 | 2013-03-15 | ||||| | タイトル | |||||| | タイトル | N-acetyltransferase 2 （NAT2）, glutatione S-transferase M1 （GSTM1）, cytochrome P450 （CYP1A1）の遺伝子多型は日本人の子宮内膜症患者の遺伝的傾向となり得るか? | ||||| | タイトル | |||||| | タイトル | Could polymorphisms of N-acetyltransferase 2 (NAT2), glutathione S-transferase M1 (GSTM1), and cytochrome P450 (CYP1A1) be responsible for genetic predisposition to endometriosis among Japanese? | ||||| | 言語 | en | ||||| | 言語 | |||||| | 言語 | eng | ||||| | 資源タイプ | |||||| | 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | ||||| | 資源タイプ | journal article | ||||| | 著者 | 飯塚, 聖子 × 飯塚, 聖子× 小杉, 好紀× 井坂, 恵一× 高山, 雅臣× Iizuka, Seiko× Kosugi, Yoshinori× Isaka, Keiichi× Takayama, Masaomi | ||||| | 書誌情報 | 東京医科大学雑誌 巻 61, 号 1, p. 59-66, 発行日 2003-04-25 | ||||| | ISSN | |||||| | 収録物識別子タイプ | ISSN | ||||| | 収録物識別子 | 0040-8905 |

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endometriosis

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