Towards a targeted non-invasive diagnosis and treatment of endometrial pathologies

Polymersome nanoparticles (NPs) are comprised of biodegradable amphiphilic block copolymers (PEG-b-PCL) and can be efficiently engineered for cell-specific targeting, drug encapsulation and delivery.The versatility of nanoparticles as delivery and reporter systems is now being exploited in clinical medicine, nanomedicine and to enhance medical healthcare.The human endometrium is associated with a number of life-altering pathophysiologies, including endometriosis.Endometriosis is a common gynaecological pathology affecting 20-30 % of women in reproductive age.Accurate non-invasive and diagnosis and treatment in the early stages of endometrial pathologies, and in particular endometriosis, is limited by the lack of sensitivity and specificity of the current detection techniques.The present study investigated the interaction