Malignant transformation of an endometriotic cyst: MDCT and MR findings

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This case report describes the malignant transformation of an endometriotic cyst into endometrioid adenocarcinoma in a 30-year-old woman. The authors utilized multidetector CT and magnetic resonance imaging to characterize the lesion, noting that MRI successfully identified soft-tissue components with strong early enhancement after gadolinium administration. Additional diagnostic indicators included high signal intensity on diffusion-weighted images and low apparent diffusion coefficient values, which are suggestive of malignancy due to restricted diffusion. This paper is centrally about endometriosis — specifically the rare complication of malignant transformation within an endometriotic cyst and its radiological detection.

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Abstract

Malignant transformation is a rare complication of endometriosis. MR criteria for diagnosis include the presence of soft-tissue components, enhanciment after contrast material administration in an endometriotic cyst. We present the multidetector CT and MR imaging findings in a case of an incidentally found endometrioid adenocarcinoma in a left-sided ovarian endometrioma, occurring in a 30-year old woman. MR imaging enabled the correct preoperative characterization of the lesion, by depicting a soft-tissue element, with strong and early enhancement after gadolinium administration. The same area had high signal intensity on diffusion-weighted images and low apparent diffusion coefficient values due to restricted diffusion, findings also strongly suggestive of malignancy.
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Malignant transformation of an endometriotic cyst: MDCT and MR findings DOI: https://doi.org/10.3941/jrcr.v5i1.435Keywords: endometriosis, endometriotic cyst, carcinoma, imaging, multidetector CT, magnetic resonanceAbstract Malignant transformation is a rare complication of endometriosis. MR criteria for diagnosis include the presence of soft-tissue components, enhanciment after contrast material administration in an endometriotic cyst. We present the multidetector CT and MR imaging findings in a case of an incidentally found endometrioid adenocarcinoma in a left-sided ovarian endometrioma, occurring in a 30-year old woman. MR imaging enabled the correct preoperative characterization of the lesion, by depicting a soft-tissue element, with strong and early enhancement after gadolinium administration. The same area had high signal intensity on diffusion-weighted images and low apparent diffusion coefficient values due to restricted diffusion, findings also strongly suggestive of malignancy.Downloads Published 2011-01-22 Issue Section Genitourinary Radiology License The publisher holds the copyright to the published articles and contents. However, the articles in this journal are open-access articles distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License, which permits reproduction and distribution, provided the original work is properly cited. The publisher and author have the right to use the text, images and other multimedia contents from the submitted work for further usage in affiliated programs. Commercial use and derivative works are not permitted, unless explicitly allowed by the publisher.

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