A Standard Virus Load Function

preprint OA: gold CC-BY-NC-ND-4.0
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Abstract

The idea is to design a simple function that can describe typical virus-load curves without solving a full virus load dynamic model. We present such a standard virus load function and validate it on data from influenza A as well as SARS-CoV-2 infection data for Macaque monkeys and humans. Further, we compare the virus load function to an established target model of virus dynamics as presented by A. Smith in [1]. This virus-load function can be used as input to higher level models for the physiological effects of a virus infection, for models for tissue damage, and to develop treatment strategies.

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europepmc
last seen: 2026-05-19T01:45:01.086888+00:00
unpaywall
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License: CC-BY-NC-ND-4.0