Fertility after discontinuation of treatment with an oral contraceptive containing 30 μg of ethinyl estradiol and 2 mg of dienogest

Inka Wiegratz, Katrin Mittmann, H. Dietrich, Thomas Zimmermann, Herbert Kühl
In: Fertility and Sterility · 2006 · vol. 85(6) , pp. 1812–1819 · doi:10.1016/j.fertnstert.2005.11.052 · PMID:16759929 · W2036128893
article OA: bronze CC0 ⤵ 2 in-corpus citations
🔓 Open OA copy View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This paper examined the return of fertility in women after stopping an oral contraceptive containing 30 μg ethinyl estradiol and 2 mg dienogest.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

ObjectiveTo examine the conception rate after cessation of a combination of 30 microg ethinyl E2 and 2 mg dienogest (EE/DNG).DesignProspective observational study.SettingPopulation-based cohort in Germany.Patient(s)Women who wished to become pregnant after cessation of an oral contraceptive (EE/DNG).Intervention(s)None.Main outcome measure(s)Cumulative conception rate within 1 year after termination of EE/DNG and time to pregnancy.Result(s)After 1 year of follow-up, the cumulative pregnancy rate was 86.6% (full analysis set; n = 706). When all participants with complete data were analyzed (n = 652), the cumulative pregnancy rate was 94.0%. More than 15% of the patients conceived in each of the first three cycles after termination of EE/DNG; the mean time to pregnancy was 3.5 cycles. The preceding duration of treatment with EE/DNG did not influence the conception rate. Except in the youngest age group (16-18 years), a certain delay was observed in the other age groups.Conclusion(s)The present prospective study revealed only a slight delay in regaining fertility during the first three cycles after cessation of EE/DNG. Thereafter, the cumulative rate of conception did not differ from that observed in fertile women who attempted to become pregnant without prior contraception.

My notes (saved in your browser only)

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cited by (2)

References (33)

Cited by (2)

Source provenance

openalex
last seen: 2026-05-14T06:08:44.784461+00:00
License: CC0 · commercial use OK