In-Human Assessment of Radio Frequency Induced Heating for Implants during MRI | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Article In-Human Assessment of Radio Frequency Induced Heating for Implants during MRI Changqing Jiang, Feng Zhang, Yichao Li, Xiaoyue Niu, Boya Xu, and 8 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-3826132/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Radio frequency induced heating of medical implants during magnetic resonance imaging (MRI) poses a serious threat to patient safety, and in vivo assessment of heating permits individualized on-site safety assessment. Based on the proton resonance frequency (PRF) thermometry, we developed a method for the in vivo evaluation of implant heating. It combined PRF signals around the implants with bioheat transfer law to reduce the interference of metal artifacts and to estimate the RF heating at implant surface. To apply this idea, we proposed a PRF-based test module consisting of processes of thermometry-heating-thermometry and verified its feasibility in phantom. Then, we validated this module for electrodes in the pig brain and investigated the effect of its parameters, as a result, the heating assessment could be achieved in approximately 2 min with a mean difference to probe measurement of 0.6 °C. Finally, we demonstrated the clinical translation in a patient with a conventional deep brain stimulation device and derived the individualized safe RF condition under 3.0T MRI. This study presents a practical solution for the in-human safety assessment of implants during MRI, which can be beneficial for both clinical and research purposes. Physical sciences/Engineering/Biomedical engineering Health sciences/Health care/Medical imaging/Magnetic resonance imaging Full Text Additional Declarations There is NO Competing Interest. Supplementary Files SupplementaryInformation.docx Supplementary Information Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-3826132","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":267754363,"identity":"23ddfffd-c385-4f51-9e85-8dd1950ddd43","order_by":0,"name":"Changqing 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