When homology fails: lessons from liver-fluke phylogenies

2025 · doi:10.32942/x24d1c
preprint OA: closed
Full text JSON View at publisher

Abstract

Misaligned sequences derail evolutionary inference. Datasets from GenBank require verification of positional homology and orientation before alignment and phylogenetic analysis. Liver-fluke case studies reveal how overlooked errors skew results, underscoring the need for rigorous checks in parasitology and all molecular research.
Full text 818 characters · extracted from oa-doi-fallback · 2 sections · click to expand

Abstract

Misaligned sequences derail evolutionary inference. Datasets from GenBank require verification of positional homology and orientation before alignment and phylogenetic analysis. Liver-fluke case studies reveal how overlooked errors skew results, underscoring the need for rigorous checks in parasitology and all molecular research. DOI https://doi.org/10.32942/X24D1C Subjects Life Sciences

Keywords

phylogenetic analysis, sequence alignment, GenBank, Fasciola hepatica, COI barcode, nad1 Dates Published: 2025-06-12 11:22 Last Updated: 2025-06-12 11:22 License No Creative Commons license Additional Metadata Conflict of interest statement: None Data and Code Availability Statement: Open data/code are not available Language: English

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. This is a recent paper (2025) — citers typically take a year or two to land, and the OpenAlex reference graph may still be filling in.

Source provenance

europepmc
last seen: 2026-05-20T01:45:00.602351+00:00