A "novel" MRI sequence for improving conspicuity and detection of hemorrhagic foci in pelvic endometriosis: Technical note

There is a growing need to develop new MRI sequences to identify and characterize hemorrhagic foci within endometriosis lesions. These foci are pivotal, as they represent a significant component of the disease's pathophysiology and have been associated with increased inflammation and angiogenesis. However, their detection within a dense, mixed background of fibrotic tissue is challenging using conventional T1W sequences, even with fat suppression. In this technical report, we propose a T1W 3D-FSE sequence specifically optimized to enhance the detection of hemorrhagic foci in endometriosis. Future clinical validation holds promise for increasing MRI accuracy, ultimately impacting patient management, outcomes, and quality of life.